African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5254

Full Length Research Paper

Antibiotic sensitivity of human genital mycoplasmas

Jafar Khan1*, Robeena Farzand1 and Pir Bux Ghumro2
  1Department of Microbiology, Kohat University of Science and Technology Kohat, 26000, NWFP, Pakistan. 2Department of Microbiology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Email: [email protected]

  •  Accepted: 24 February 2010
  •  Published: 04 May 2010

Abstract

 

The therapeutic failure of antimycoplasma drugs, subject to resistance is vital for specific microbiological investigation to overcome urogenital diseases among women. The susceptibility of 5 Mycoplasma hominis strains and 11 strains ofUreaplasma urealyticum were studied against six antibiotics namely: minocycline, lincomycin, erythromycin, tetracycline, doxycycline and rosaramicin. Both M. hominis and Ureaplasmas strains were highly resistant to tetracycline. It was observed that both rosaramicin and minocycline were active growth inhibitors for Ureaplasmas. However, erythromycin and lincomycin showed differential growth inhibitory patterns for M. hominis and Ureaplasma strains. In comparison, the minocycline and doxycycline exhibited similar antibiotic activity againstUreaplasma and M. hominis. The in vitro antibiotic sensitivity analysis for rosaramicin and erythromycin was also noted to be at the same level for all the isolates.

 

Key words: Mycoplasma hominis, Ureaplasma urealyticum, antibiotic sensitivity, drug resistance.