African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5249

Full Length Research Paper

Assessment of drugs pressure on Escherichia coli and Klebsiella spp. uropathogens in patients attending Abobo-Avocatier Hospital, North of Abidjan (Côte d’Ivoire)

Innocent Allepo ABE
  • Innocent Allepo ABE
  • Laboratoire de Génétique, UFR Biosciences, Université Félix Houphouët-Boigny, 22 BP 582 Abidjan 22, Côte d’Ivoire.
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Mathurin KOFFI
  • Mathurin KOFFI
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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Paulin Didier SOKOURI
  • Paulin Didier SOKOURI
  • Laboratoire de Génétique, UFR Biosciences, Université Félix Houphouët-Boigny, 22 BP 582 Abidjan 22, Côte d’Ivoire.
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Bernardin Ahouty AHOUTY
  • Bernardin Ahouty AHOUTY
  • Laboratoire de Génétique, UFR Biosciences, Université Félix Houphouët-Boigny, 22 BP 582 Abidjan 22, Côte d’Ivoire.
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Martial Kassi N’DJETCHI
  • Martial Kassi N’DJETCHI
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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Siriki SIMARO
  • Siriki SIMARO
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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Edwige Abla SOKOURI
  • Edwige Abla SOKOURI
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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Barkissa TRAORE
  • Barkissa TRAORE
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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Thomas Konan KONAN
  • Thomas Konan KONAN
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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William YAVO
  • William YAVO
  • Institut National de Santé Publique (INSP), 01 BPV 34 Abidjan-Côte d'Ivoire.
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Sanogo Abiba TIDOU
  • Sanogo Abiba TIDOU
  • Unité de Recherche en Génétique et Epidémiologie Moléculaire (URGEM), Laboratoire de Biodiversité et Gestion durable des Ecosystèmes Tropicaux, UFR Environnement, Université Jean Lorougnon Guédé, BP 150 Daloa, Côte d’Ivoire.
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Simon-Pierre N’GUETTA
  • Simon-Pierre N’GUETTA
  • Laboratoire de Génétique, UFR Biosciences, Université Félix Houphouët-Boigny, 22 BP 582 Abidjan 22, Côte d’Ivoire.
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  •  Received: 07 July 2019
  •  Accepted: 09 October 2019
  •  Published: 30 November 2019

Abstract

The problem of antibiotic resistance of uropathogens appears in Abobo municipality to be worsening because of the overuse and misuse of antibiotics. This study aims to assess the impact of drugs pressure on uropathogenic Escherichia coli and Klebsiella spp. strains isolated from patients attending Abobo-Avocatier Hospital. The study was conducted in patients suffering from urinary tract infection. Urine samples of patients were collected; culture and antibiogram using the Kirby-Bauer disc diffusion method were performed. The overall prevalence was 31.1% with a significant difference between males and females (p = 0.01). The highest susceptible age group of patients to UTI was 21-45 years (33%). E. coli and Klebsiella spp were the predominant bacteria among isolated Gram negative. Up to 70% of the isolates of both uropathogens were resistant to Penicillins, Tetracyclines and Ampicillin-Sulbactam. Imipenem was the most active antibiotic on these uropathogens. Quinolones showed a better activity on Klebisiella spp. strains than those of E. coli. The high value of the Multiple Antibiotic Resistance Index and the rate of multi-resistance from this site suggest the need for continuous monitoring of antibiotic susceptibility profile of bacteria implicated in UTI prior to antibiotic prescription in order to ensure optimal and desired treatment.

 

Key words: Urinary tract infections, uropathogens, multidrug resistance, Abidjan, Côte   d’Ivoire.

Copyright © 2025 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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