African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5077

Article in Press

Evaluation of Enterobacteriaceae dominance in clinical samples and their drug profiling

Muhammad Bilal Habib, Noreen Sher Akbar

  •  Received: 10 March 2020
  •  Accepted: 20 July 2020
Infections caused by Enterobacteriaceae is one of the major problems faced by people regarding antibiotic resistance. This study was aimed to check the prevalence and antibiogram of Enterobacteriaceae isolated from different clinical samples. This Prospective study was carried out in National Institute of Health, Islamabad. One hundred and ten samples were analyzed out of which positive Enterobactereciae samples were sixty-one. Samples were inoculated on blood and MacConkey agar. With the help of gram staining and biochemical testing using API 20E, the isolates were identified. Antimicrobial susceptibility testing of Enterobacteriaceae against different antimicrobial drugs was done by using Kirby-bauer disk diffusion method. Total samples analyzed were 110, and positive samples for Enterobacteriaceae were 61. The highly sensitive drug to E. coli, Klebsiella pneumonia, Salmonella typhi and Salmonella paratyphi was Imipenem, whereas Augmentin and Ampicillin was highly resistant. The highly sensitive drug to Acinetobacter was Tigecycline and Colistin, whereas Imipenem was highly resistant. This study also showed that E. coli was the most common Enterobacter isolated and has high prevalence as compared to other Enterobacteriaceae species. Females were more prone to infections caused by Enterobacteriaceae species than the Males.

Keywords: Enterobacteriaceae, Prevalence, E. coli, Klebsiella pneumoniae, Salmonella typhi, Salmonella paratyphi, Acinetobacter.