Ethanolic and aqueous extracts of Cassia singueana Del. leaves were screened for their antimicrobial activity against Staphylococcus aureus, Streptococcus pyogen,Escherichia coli, Salmonella typii and Shigella dysentery. The result indicated that the extracts inhibited the growth of one or more test pathogens. The ethanolic extract showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, saponins, alkaloids, glycosides, flavonoids, carbohydrate and terpenes. The minimum inhibitory concentration (MIC) ranges from 1.0 x 104 to 4 x 103 µg/mI.
Key words: Cassia singueana, Caesalpiniaceae, leaf extracts, antimicrobial activity, phytoconstituents.
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