African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 357

Full Length Research Paper

Preliminary phytochemical and antimicrobial screening of the leaf extract of Cassia singueana Del

Olusola Adeyanju1, Olajide Olutayo O1*, Afolayan Michael1 and Khan IZ2
1Chemistry Advanced Laboratory, Sheda Science and Technology Complex, P.M.B 186, Garki, Abuja, Nigeria. 2Department of Chemistry, University of Maiduguri, P.M.B 1069, Maiduguri, Borno State, Nigeria
Email: [email protected]

  •  Accepted: 17 February 2011
  •  Published: 30 April 2011


Ethanolic and aqueous extracts of Cassia singueana Del. leaves were screened for their antimicrobial activity against Staphylococcus aureusStreptococcus pyogen,Escherichia coli, Salmonella typii and Shigella dysentery. The result indicated that the extracts inhibited the growth of one or more test pathogens. The ethanolic extract showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, saponins, alkaloids, glycosides, flavonoids, carbohydrate and terpenes. The minimum inhibitory concentration (MIC) ranges from 1.0 x 10to 4 x 10µg/mI.


Key words: Cassia singueanaCaesalpiniaceae, leaf extracts, antimicrobial activity, phytoconstituents.