Abstract

This paper deals with the synthesis and characterization of a novel ionic liquid using green chemicals such as tetra-butyl ammonium chloride (TBA) and 2-acrylamido-2-methylpropanesulphonate (AMPS) via an anion metathesis reaction and characterization by ¹H-NMR technique. Also, this ionic liquid was used to catalyze Mannich reactions under solvent free conditions to afford the corresponding β- amino carbonyl compound (Mannich base) in excellent yields in shorter span of time than those of the conventional methods. This work has proven to be a very efficient and selective protocol for Mannich condensation reactions as it involves a simple work-up procedure, absence of by-products, recyclability of the catalyst and using greener chemicals that are environmentally and ecologically benign.

Key words: Ionic liquid, TBA-AMPS, Mannich base, condensation reaction, metathesis reaction, solvent free condition.