African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 347

Full Length Research Paper

Chemical modification of cellulose from palm kernel de-oiled cake to microcrystalline cellulose and its evaluation as a pharmaceutical excipient

Ezea Vincent Ndika
  • Ezea Vincent Ndika
  • Department of Applied Biochemistry, Faculty of Biological Sciences, Nnamdi Azikiwe University Awka, Anambra State, Country, Nigeria.
  • Google Scholar
Umerie Sunday Chidozie
  • Umerie Sunday Chidozie
  • Department of Applied Biochemistry, Faculty of Biological Sciences, Nnamdi Azikiwe University Awka, Anambra State, Country, Nigeria.
  • Google Scholar
Ubaoji Kingsley Ikechukwu
  • Ubaoji Kingsley Ikechukwu
  • Department of Applied Biochemistry, Faculty of Biological Sciences, Nnamdi Azikiwe University Awka, Anambra State, Country, Nigeria.
  • Google Scholar


  •  Received: 31 January 2019
  •  Accepted: 02 July 2019
  •  Published: 31 July 2019

References

Ambjornson HA, Schenzel K, Germgard U (2013). Carboxylmetyl cellulose produced at different mercerization conditions and characterized by NIR FT Raman Spectroscopy in combination with multivariate analytical methods. Biological Resources 8(2):1918-1932.
Crossref

 

Banker GS, Anderson NR (1987). In: The Theory and Practice of Industrial Pharmacy, third ed. Lachman L, Lieberman HA, Kanig JL, editors. Varghese Publishing House; Mumbai pp. 293-299.

 

Bolhuis GK, Chowhan ZT (1996). Materials for direct compaction. In: Alderborn G, Nystrom C, editors. Pharmaceutical Powder Compaction Technology. New York: Merkcel Dekker Inc: 419-500.
Crossref

 

Caramella C (1991). Novel methods for disintegrant characterisation, part 1. Pharmaceutical Technology 3:48-56.

 

Carr RL Jr (1965). Evaluating flow properties of solids. Journal of Chemical Engneering 72:163-168.
Crossref

 

Doelker E, Mordier D, Iten H, Humbert-Droz P (1987). Comparative tableting properties of sixteen microcrystalline celluloses. Drug Development and Industrial Pharmacy 13(9-11):1847-1875.
Crossref

 

Dong XM, Revol JF, Gray DG (1998), Effect of microcrystalline preparation conditions on the formation of colloid crystals of cellulose. Cellulose 5(1):19-32.
Crossref

 

Evans WC (1989). Trease and Evans' Pharmacognosy. 13th ed. BailliereTindall pp. 339-377.

 

Haque SM, Chowdhury AA, Rana AA, Masum SM, Ferdous T, Rashi MA, Sarker M, Karim MM (2015). Synthesis of microcrystalline cellulose from pretreated cotton obtained from Bombax ceiba L. and its characterization. Bangladesh Journal of Scientific and Industrial Research 50(3):199-204.
Crossref

 

Hausner HH (1967). Friction conditions in a mass of metal powders. International Journal of Powder Metall 3:7-13.

 

Jafar EK, Mohammand N, Ahmad S, Hossein C, Nima SM, Hassan N (2011). Studying of effect of the age in Eucalyptus Camaldulensis species on wood chemical compounds used in pulping process. American-Eurasian Journal of Agricultural and Environmental Sciences 6:17-39.

 

Jahan M, Saeed A, He Z, Ni Y (2011). Jute as raw material for preparation of microcrystalline cellulose. Cellulose 18(2):451-459.
Crossref

 

Kornblum SS, Stoopak SB (1973). A new tablet disintegrant agent: cross linked polyvinylpyrollidone. Journal of Pharmaceutical Sciences 62:43-9.
Crossref

 

Kumar V, Sanjeev HK, Gilbert SB (2001). Compression, Compaction, and Disintegration Properties of Low Crystallinity Celluloses Produced Using Different Agitation
Crossref

 

Landin M, Martinez-Pacheco R, Gomez-Amoza JL, Souto C, Concheiro A, Rowe RC (1993). Effect of batch variation and source of pulp on the properties of microcrystalline celluloseInternational Journal of Pharmaceutics 91:133-41.
Crossref

 

Latif A, Anwar T, Noor S (2007). Two step synthesis and characterization of carboxylmethyl cellulose from rayon grade woods pulp and cotton linter. Journal of Chemistry 29(2):143-150

 

Leppänen K, Pirkkalainen K, Penttilä P, Sievänen J, Kotelnikova N, Serimaa R (2010). Sami-angle x-ray scattering study on the structure of microcrystalline cellulose. Journal of Physics pp. 247-249.
Crossref

 

Leppanen K, Seppo A, Tarkkeli M, Matti K, Nina K, Ritava S (2009). Structure of cellulose and microcrystalline cellulose from various wood species and flax studied by X-ray scattering: Journal of Springer Science + busnicess Media pp. 147-152.

 

Mark HF, Bikales NM, Overberger CG, Meufe G (1985). Encyclopedias of polymer science and engineering. John wiley and Sons, New York 3:326-340.

 

Monika T, Ajay KS, Amit RS (2015). Physicochemical Parameter of Microcrystalline Cellulose and the Most Acceptability in Pharmaceutical Industries. Journal of Innovations in Pharmaceuticals and Biological Sciences 2(4):570-578.

 

Nuruddin M, Chowdhury A, Haque SA, Rahma A, Farhad SF, Sarwar MJ, Quaiyyum A (2012). Extraction and characterization of cellulose micrfibrils from agricultural wastes in an integrated biorefinery initiative. Journal of Cellulose chemistry and technology 1:17-20.

 

Ohwoavworhua FO, Adelakun TA (2010). Non-wood Fibre Production of Microcrystalline Cellulose from Sorghum caudatum: Characterisation and Tableting Properties. Indian Journal of Pharmaceutical Sciences 72(3):295-301.
Crossref

 

Ohwoavworhua FO, Kunle OO, Ofoefule SI (2004). Extraction and characterization of microcrystalline cellulose derived from Luffacylindrica plant. African Journal of Pharmaceutical Research and Development 1:1-6.

 

Ohwoavworhua FO, Ogah E, Kunle OO (2005).Preliminary investigation of physicochemical and functional properties of alpha cellulose obtained from waste paper - A potential pharmaceutical Excipient. Journal of Raw Materials Research 2:84-93.

 

Peck GE, Baley GJ, Mcurdy VE, Banker GS (1989). Tablet formulation and design. In: Lieberman HA, Lechman L, Schwarz JB (eds) Pharmaceutical dosage froms. 1 Mercel Dekker, New York, 1:75-130.

 

Pickard MD (2005). By-products utilization. In: Bailey's industrial oil products. Edible Oil and Fat Products: Products and applications. Wiley-Interscience 4(6):46-66
Crossref

 

Rates During their Regeneration from Phosphoric Acid Solutions. AAPS PharmSciTech 1:245-250.

 

Roshni SV, Yamini DS (2015). Production of Micro Crystalline Cellulose from Corn Husk and Its Evaluation as pharmaceutical Excipient. Department of pharmaceutics and pharmaceutical technology, L.M. College of Pharmacy, Ahmedabad, Gujarat, India 2(11):2321-2705.

 

Sakurada I, Nukushina Y, Ito T (1962). Experimental Determination of Elastic Modulus of Crystalline Regions in Oriented Polymers, Journal of Polymer Science 57(165):651-660.
Crossref

 

Setu MNI, Mia MY, Lubna, NJ, Chowdhury AA (2014). Preparation of Microcrystalline Cellulose form Cotton and its Evaluation as Direct Compressible Excipient in the Formulation of Naproxen Tablets, Dhaka. University Journal of Pharmaceutical Sciences 13(2):187-192.
Crossref

 

Shangraw RF (1984). Advantages and disadvantages of wet granulation and direct compression processes for making tablets. Modern Granulation, Tableting and Capsule Technology, Centre for Professional Advancement. Amsterdam, Netherlands. Cellulose 5(1):19-32.

 

Shokri J, Adibkia K (2013). Application of cellulose and cellulose derivatives in pharmaceutical industries. Journal of Intech open science 1:855-862.
Crossref

 

Soppela I, Airaksinen S, Matti M, Tenho M, Juha H, Heikki R, Jouko Y, Niklas S (2010). Investigation of the powder flow behavior of binary mixtures of microcrystalline cellulose and paracetamol. Journal of Excipients and Food Chemicals 1:55-67.

 

Stamm AF (1964). Wood and Cellulose Science. New York: The Ronald Press Company pp. 132-165.

 

Staniforth JN (1996). Powder flow. In: Aulton ME, editor. Pharmaceutics-The Science of Dosage form Design. London: Churchill Livingston pp. 600-615.

 

Thoorens G, Krier FB, Evrard CB (2014). Microcrystalline cellulose, a direct compression binder in a quality by design environment-A review. International Journal of Pharmaceutics 473:64-72.
Crossref

 

United States Pharmacopoeia (2004). British Pharmacopoeia 2004.

 

Voravadee S, Pranut P, Duandao A (2016). Preparation and characterization of microcrystalline cellulose from cellulose based-agro waste. Journal of Engineering and Applied Science 11(12):2566-2572.

 

Yakubu AT, Mumar SSD (2011). Chemical modification of microcrystalline cellulose: improvement of barrier surface properties to enhance surface interaction with some synthetic polymers for biodegradable packing material processing and application in textile, food and pharmaceutical industry: Journal of Pelagia Research Library Advance In Applied Research 2:532-540.