African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 353

Table of Content: 29 February, 2012; 6(4)

February 2012

Chemoselective 3-O-alkylation of L-ascorbic acid under phase transfer catalysis

A detailed investigation for synthesis of chemo-selective 3-O-alkylation of L-ascorbic acid under phase transfer catalysis has been carried out. All the compounds were fully characterized by infra red (IR), NMR and microanalysis. Reaction of 5,6-O-isopropylidene-L-ascrobic acid with one equivalent of corresponding alkylating agent and tetrabutyl ammonium iodide as phase transfer catalyst in biphasic system (water:ethyl...

Author(s): Shankar Ramchandra Thopate and Santosh Rajaram Kote  

February 2012

In vitro antimycobacterial studies on the leaf extracts and fractions of Pavetta crassipes K. Schum

Tuberculosis is a major public health threat and Nigeria has the world’s fifth largest tuberculosis burden, with nearly 311,000 estimated cases annually. Mycobacterium tuberculosis, the causative organism, has acquired resistance against most of the current chemotherapy, thereby calling for the urgent development of new antituberculosis drugs. Preliminary phytochemical and antimycobacterial studies were...

Author(s): Nneka N. Ibekwe, Abayomi T. Orishadipe, Helena Boshoff, Akinbo A. Adesomoju, Joseph I. Okogun and Clifton E. Barry