African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2162

Full Length Research Paper

Effect of Butea monosperma (Lamk.)Taub. (Palas papra) fruit on blood glucose and lipid profiles of normal and diabetic human volunteers

Muhammad Shoaib Akhtar1*, Fizza Naeem2, Faqir Muhammad3 and Nighat Bhatty2
1Department of Pharmacy, Sargodha University, Pakistan. 2Department of Home Economics, University of Agriculture, Faisalabad – 38040, Pakistan. 3Department of Physiology and Pharmacology, University of Agriculture, Faisalabad – 38040, Pakistan.
Email: [email protected]

  • Article Number - 12928CB26568
  • Vol.4(8), pp. 539 - 544, August 2010
  •  Accepted: 20 August 2010
  •  Published: 31 August 2010

Abstract

The aim of this study was to evaluate the effect of Butea monosperma(Lamk.)Taub on blood glucose and lipid profiles in normal and diabetic human volunteers. This study indicated a significant decrease (P < 0.05) in 2 h post- prandial blood glucose (mg/dl) on 21st day in the diabetic subgroups treated with 2 g (194.2 ± 27.01 vs. 172.2 ± 20.37) and 3 g (203.0 ± 19.49 vs. 165.7 ± 48.83) of powdered B. monosperma (Lamk.)Taub. A significant decrease in total cholesterol (mg/dl) was observed in normal (179.75 ± 4.42 vs. 131.25 ± 8.5) and diabetic (219.2 ± 13.97 vs. 143.7 ± 12.93) subgroups on day 21st post treatment. Both normal (560.2 ± 13.14 vs. 393.7 ± 8.38 mg/dl) and diabetic groups (594.7 ± 8.60 vs. 431.2 ± 17.97 mg/dl) exhibited a significant decrease in total lipids on day 21st. This study indicates that B. monosperma (Lamk.)Taub might possess important hypoglycemic and hypolipidemic properties. 

 

Key words: Butea monosperma, diabetes, lipids, cholesterol, humans.

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