African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2296

Full Length Research Paper

Guidelines for rational use of drug based data extracted from the APURMED application in Burkina Faso

Tinguéri L. B.
  • Tinguéri L. B.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Ki A.
  • Ki A.
  • Direction de la Promotion et de l’Education pour la Santé / Ministère de la santé, Directorate of Health Promotion and Education / Ministry of Health 03 BP: 7027 Ouagadougou 03, Burkina Faso.
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Nikiema S.
  • Nikiema S.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Kafando H.
  • Kafando H.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Bationo B. G.
  • Bationo B. G.
  • Direction des Laboratoires de Biologie Médicale / Ministère de la santé, Directorate of Medical Biology Laboratories / Ministry of Health 03 BP: 7027 Ouagadougou 03, Burkina Faso.
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Coulibaly M.
  • Coulibaly M.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Zan I.
  • Zan I.
  • Association VIVA INNOVA 09 BP: 1805 Ouagadougou 09, Burkina Faso.
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Rouamba M.
  • Rouamba M.
  • Agence Nationale de Régulation Pharmaceutique/ Ministère de la santé, National Pharmaceutical Regulatory Agency / Ministry of Health 03 BP: 7027 Ouagadougou 03, Burkina Faso.
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Zoungrana A. B.
  • Zoungrana A. B.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Semdé S.
  • Semdé S.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Zohoncon T. M.
  • Zohoncon T. M.
  • Faculté des Sciences de la Santé/ Université Saint Thomas d’Acquin, Faculty of Health Sciences / Saint Thomas Aquinas University 06 BP: 10212 Ouagadougou 06, Burkina Faso.
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Somé P. C.
  • Somé P. C.
  • Laboratoire d’Informatique Médicale, Medical Informatics Laboratory 01 BP: 2519 Ouagadougou 01, Burkina Faso.
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Bonkoungou V.
  • Bonkoungou V.
  • Ordre national des pharmaciens du Burkina Faso, National Order of Pharmacists of Burkina Faso 06 BP: 9037 Ouagadougou 06, Burkina Faso.
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Ouédraogo M.
  • Ouédraogo M.
  • Université Joseph Ki-Zerbo, Joseph Ki-Zerbo University 03 BP: 7021 Ouagadougou 03, Burkina Faso.
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  •  Received: 13 October 2024
  •  Accepted: 05 November 2024
  •  Published: 30 November 2024

Abstract

The major constraint of insufficient resources limits the availability and accessibility of medicine. Fortunately, proper use of available medicinal resources could contribute to greater efficiency within the health system. This study, using data extracted from the APURMED application, aims to guide the rational use of drugs in practice within Burkina Faso. Treatments for infectious and non-communicable diseases represent a significant portion of therapeutic concerns (50.83%, n=860). These concerns should be addressed to adapt training and professional practices to the context. Mastery of drugs with potential equivalents (14.15%, n=2579) could enhance drug substitution and identification of therapeutic redundancies. Drug-related risks stem from either the patient (risk factors, organ insufficiencies, or vulnerable physiology) or the drug itself (intrinsic risk), as well as unfavorable drug combinations (hidden risks). Any drug could pose a risk based on the patient profile (such as allergies). More than half of the drugs (57.21%, n=860) could lead to unfavorable combinations. Prescription analysis is necessary to identify and mitigate these risks by using relevant clinical and biological data, select the safest drug or combination, reducing the number of prescribed medications, avoiding therapeutic redundancies, advising the patient on correct dosage, and monitoring for drug risks.

Key words: APURMED, data extraction, rational use of drug, avoidable risk, Burkina Faso.