African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2195

Full Length Research Paper

The role of intralesional Pingyangmycin in the treatment of nasal polyp in aged population

Zhenghui Wang, Xianghong Zhang*, Baoshu Li, Fang Quan and Miaoli Yang
Department of Otolaryngology-Head and Neck Surgery, the Second Hospital, Xi’an JiaoTong University, Xi’an 710004, China.
Email: [email protected], [email protected]

  •  Accepted: 03 April 2012
  •  Published: 15 August 2012


This study is to investigate the effect of intralesional Pingyangmycin injection in nasal polyp. 82 patients with nasal polyp were treated with intralesional Pingyangmycin injection from September 2001 to September 2006. After a minimum follow-up of 2 years, 67 patients (81.7%) developed 76 to 100% regression in their lesions; 17 patients (18.3%) had 51 to 75% regression in their lesions. No changes in renal function or cytopenias were encountered and no changes were found with chest X-ray during the course of therapy. Thus, intralesional injection of Pingyangmycin seemed to be an effective, safe and inexpensive method to treat nasal polyp, especially in patients not suitable for surgeries.


Key words: Pingyangmycin, nasal polyp, intralesional, aged.