This study is to investigate the effect of intralesional Pingyangmycin injection in nasal polyp. 82 patients with nasal polyp were treated with intralesional Pingyangmycin injection from September 2001 to September 2006. After a minimum follow-up of 2 years, 67 patients (81.7%) developed 76 to 100% regression in their lesions; 17 patients (18.3%) had 51 to 75% regression in their lesions. No changes in renal function or cytopenias were encountered and no changes were found with chest X-ray during the course of therapy. Thus, intralesional injection of Pingyangmycin seemed to be an effective, safe and inexpensive method to treat nasal polyp, especially in patients not suitable for surgeries.
Key words: Pingyangmycin, nasal polyp, intralesional, aged.
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