African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2207

Full Length Research Paper

Antimicrobial potential evaluation of hydroethanolic extracts of the species Anacardium occidentale Linn.

Edilane Rodrigues Dantas Araujo
  • Edilane Rodrigues Dantas Araujo
  • Faculty of Pharmacy - Federal University of Rio Grande do Norte. RUA GAL GUSTAVO C FARIAS, S/N, NATAL - RN, Brazil. +55 84 3215.4341
  • Google Scholar
Silvana Maria Zucolotto Langassner
  • Silvana Maria Zucolotto Langassner
  • Faculty of Pharmacy - Federal University of Rio Grande do Norte. RUA GAL GUSTAVO C FARIAS, S/N, NATAL - RN, Brazil. +55 84 3215.4341
  • Google Scholar
Geraldo Barroso Cavalcanti Júnior
  • Geraldo Barroso Cavalcanti Júnior
  • Faculty of Pharmacy - Federal University of Rio Grande do Norte. RUA GAL GUSTAVO C FARIAS, S/N, NATAL - RN, Brazil. +55 84 3215.4341
  • Google Scholar
Dany Gerard Kramer
  • Dany Gerard Kramer
  • Faculty of Health Sciences of the Trairi (FACISA) - Federal University of Rio Grande do Norte. Avenida Rio Branco S/N, Santa Cruz / RN. Brazil + 55 84 32912411
  • Google Scholar


  •  Received: 05 February 2016
  •  Accepted: 06 June 2016
  •  Published: 29 July 2016

Abstract

The species Staphylococcus aureus and Escherichia coli have shown increased antimicrobial resistance, which can be overcome with plant extracts, in view of their molecular complexity, for example extracts of Anacardium occidentale Linn (cashew). The objective was to evaluate the in vitro antimicrobial activity of cashew stem bark extract. Samples were collected in Santa Cruz / RN / Brazil, and after dried and crushed, the extract was prepared by maceration with ethanol: water solution (70:30 v / v) at a ratio (1:10 w / v ) for 7 days. The filtrate was reduced by rotary evaporator and the resulting frozen. Extracts were characterized by Thin Layer Chromatography (TLC) and tested for antimicrobial activity in various concentrations (200 to 6.25 mg / ml) by diffusion disk. TLC testing indicated that the plant extract has phenolics, tannins mainly responsible for the pharmacological properties. The minimum inhibitory concentration was determined at 12.5 mg / ml only for S. aureus.

Key words: Cashew, antimicrobial activity, S. aureus.