African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2201

Full Length Research Paper

Biological screening of ethyl acetate extract of Hedera nepalensis stem

Ghias Uddin, Ashfaq Ahmad Khan*, Muhammad Alamzeb, Saqib Ali, Mamoon-Ur-Rashid Anwar Sadat, Muhammad Alam, Abdul Rauf and Wali Ullah
Institute of Chemical Sciences, University of Peshawar, Khyber Pakhtunkhwa (KPK), Peshawar, Pakistan.
Email: [email protected]

  •  Accepted: 03 October 2012
  •  Published: 15 November 2012

Abstract

Hedera nepalensis is commonly used in folk medicines for the treatment of cough and other human ailments; therefore it was selected for phytochemical and antimicrobial screening. Its phytochemical screening showed the presence of different classes of secondary metabolites. The ethyl acetate extract of its stem showed the presence of steroids, terpenoids, saponins and flavonoids. Terpenoids and flavonoids were present in chloroform and ethyl acetate fractions, steroids were present in chloroform and ethyl acetate crude extract. Ethyl acetate and chloroform fractions were found most active. Among the organisms tested, Escherichia coli was the most sensitive to the plant extract as it displayed the greatest inhibitory zone (20:0 mm).

 

Key words: Phytochemical screening, Hedera nepalensis, antibacterial activity.