African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2201

Full Length Research Paper

Jatropha dioica, an Aztec plant with promising pharmacological properties: A systematic review

Agustina Ramírez-Moreno
  • Agustina Ramírez-Moreno
  • Faculty of Biological Sciences, Autonomous University of Coahuila, Carr. Torreón-Matamoros, km 7.5, CP.27276. Torreón, Coahuila, Mexico.
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Dealmy Delgadillo-Guzmán
  • Dealmy Delgadillo-Guzmán
  • Department of Pharmacology, Faculty of Medicine, Torreon Unit, Autonomous University of Coahuila, Torreón, Coahuila, Mexico.
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Verónica Bautista-Robles
  • Verónica Bautista-Robles
  • Food and Nutrition, Faculty of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brasil.
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Jolanta E Marszalek
  • Jolanta E Marszalek
  • Faculty of Biological Sciences, Autonomous University of Coahuila, Carr. Torreón-Matamoros, km 7.5, CP.27276. Torreón, Coahuila, Mexico.
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Hady Keita
  • Hady Keita
  • Division of Postgraduate Studies, University of Sierra Sur, Miahuatlán de Porfirio Díaz, Oaxaca, CP. 70805, Mexico.
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Ansoumane Kourouma
  • Ansoumane Kourouma
  • Department of Pharmaceutical Sciences, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
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Sergio Alberto Ramírez García
  • Sergio Alberto Ramírez García
  • Division of Postgraduate Studies, University of Sierra Sur, Miahuatlán de Porfirio Díaz, Oaxaca, CP. 70805, Mexico.
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Jesús Rafael Rodríguez Amado
  • Jesús Rafael Rodríguez Amado
  • Food and Nutrition, Faculty of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brasil.
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José Carlos Tavares-Carvalho
  • José Carlos Tavares-Carvalho
  • Drug Research Laboratory, Federal University of Amapá, Rodovia Juscelino Kubitschek, km 2, Jardim Marco Zero, CEP: 68903-419 Macapá, AP, Brazil.
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  •  Received: 01 April 2020
  •  Accepted: 10 June 2020
  •  Published: 31 July 2020

Abstract

Few pharmacological and toxicological studies have been conducted to demonstrate the usefulness and safety of using the Jatropha dioica extract. The aim of this study was to update the state of the art on the chemical composition, pharmacology, and toxicology of the species J. dioica, to find new possible applications. A search of different databases was carried out on the internet, specifically in Science Direct, PubMed, EBSCO, SCOPUS, Web of Science and Springer Link, with the keyword being “Jatropha dioica”. Despite the limited results with regard to the plant toxicity, it was shown that the extract to use is innocuous. In addition, it was found that J. dioica could be employed as an antioxidant, antibiotic, antifungal, or antiviral agent. Although promising, more scientific research is needed to further validate the ethno pharmacological use of the J. dioica extracts.

Key words: Jatropha, toxicity, chemical composition, ethno pharmacology, plants medicinal.