African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 15 February 2014; 8(6)

February 2014

Antibacterial activity and cellulose acetate electrophoresis in monitoring collagen hydrogels modified with saccharides

Antimicrobial compounds of plant origin (for example fucoidan, lignans, β-glucans, polyphenols), occurring in roots, leaves, flowers and fruits of plants, have demonstrated antitumor antioxidant, antibacterial or antifungal activities. The samples of collagen hydrogels or saccharide incorporated collagen hydrogels (for example, fucoidan from the bladderwrack or β-glucans from the oatmeal fibre) were examined....

Author(s): Anna Pielesz and Alicja Machnicka

February 2014

A new multivariate similarity factor for in vitro therapeutic equivalence assessment

Pharmaceutical equivalence is an important issue in the regulatory approval of generic and similar drug products, particularly for those that will not be tested for bioequivalence. However, there is no scientific approach that provides us an objective measure of quality and similarity of the results obtained for testing (generic or similar) and branding drug products simultaneously. This paper describes a new...

Author(s): Marcus Augusto Lyrio Traple, Rogério Takao Okamoto, Rosa Noriko Yamamoto, Terezinha de Jesus Andreoli Pinto and Felipe Rebello Lourenço

February 2014

E-Cadherin, beta-catenin and HER2 expression in prostate cancer tissues with perineural invasion and their correlation with Gleason score: A preliminary study

Prostate cancer (PC) is the most common malignant tumor in men. Early identification of prostate cancer may result in improved cure rates and increased life expectancies. Gleason score and clinical range at the time of diagnosis are important factors to predict prognosis and outcome after therapy but additional accurate and reliable biomarkers are warranted. Few biomarkers of prostate cancer have been successfully...

Author(s): Sandra Regina Bonfim Rodrigues, Maylla Yabiko, Rafael Bazan Thomaz, Therese Theodoro, Beatriz Alves , Ligia Ajaime Azzalis, Edimar Cristiano Pereira, Virginia Berlanga Campos Junqueira, Roseli Corazzini, Fernando Adami and Fernando Luiz Affonso Fonseca,