February 2014
A new multivariate similarity factor for in vitro therapeutic equivalence assessment
Pharmaceutical equivalence is an important issue in the regulatory approval of generic and similar drug products, particularly for those that will not be tested for bioequivalence. However, there is no scientific approach that provides us an objective measure of quality and similarity of the results obtained for testing (generic or similar) and branding drug products simultaneously. This paper describes a new...
February 2014
E-Cadherin, beta-catenin and HER2 expression in prostate cancer tissues with perineural invasion and their correlation with Gleason score: A preliminary study
Prostate cancer (PC) is the most common malignant tumor in men. Early identification of prostate cancer may result in improved cure rates and increased life expectancies. Gleason score and clinical range at the time of diagnosis are important factors to predict prognosis and outcome after therapy but additional accurate and reliable biomarkers are warranted. Few biomarkers of prostate cancer have been successfully...
February 2014
Antibacterial activity and cellulose acetate electrophoresis in monitoring collagen hydrogels modified with saccharides
Antimicrobial compounds of plant origin (for example fucoidan, lignans, β-glucans, polyphenols), occurring in roots, leaves, flowers and fruits of plants, have demonstrated antitumor antioxidant, antibacterial or antifungal activities. The samples of collagen hydrogels or saccharide incorporated collagen hydrogels (for example, fucoidan from the bladderwrack or β-glucans from the oatmeal fibre) were examined....
Advertisement
Advertisement
