African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2248

Table of Content: 15 January, 2014; 8(2)

January 2014

Evaluation of spermatogenesis in prepubertal albino rats with date palm pollen supplement

It is suggested that Date Palm Pollen (DPP) increases the concentration of testosterone, follicle stimulating hormone, and luteinizing hormone in rats. We therefore planned this study to examine the effect of DPP on spermatogenesis using prepubertal rats. 4-day old rats were randomly divided into four groups of 12 pups each (Control I, Experimental I, Control II, and Experimental II). Experimental groups I and II were...

Author(s): Salman Iftikhar, Munazza Ahmad, Hina Muhammad Aslam, Tahir Saeed, Yasir Arfat and Gul-E- Nazish

January 2014

An overview of ethnopharmacological properties of Boerhaavia diffusa

Herbal medicines are used by traditional healers since hundreds of years, and medicinal plants are imperative reserve for traditional and herbal industry. This practice is in vogue since ancient times. Over 80,000 species of plants are used globally for their medicinal uses. Boerhaavia diffusa is one of the distinguished medicinal plants used to treat large number of human ailments. The plant in whole or its parts...

Author(s): Humayun Riaz, Syed Atif Raza, Shahzad Hussain, Sidra Mahmood and Farnaz Malik

January 2014

Antimicrobial and antioxidant evaluation of various parts of Cola milleni K. Schum plant

The methanol extracts of the various plant parts were screened for anti-oxidant activity by thin layer chromatography using 2,2-diphenyl-1-dipicrylhydrazyl (DPPH) while their in vitro antimicrobial evaluation were determined by agar diffusion method and bioautographic technique using Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa as test organisms; aqueous solvent served as...

Author(s): Orisakeye, O. T. and Ojo, A. A.

January 2014

Could neuroplasticity be an answer to different antidepressants efficacy among individuals?

Neuroplasticity is nervous system changes that occur in response to experience. Different individuals may have different neuroplasticity due to their different experiences. Even monozygotic twins may develop different neuroplasticity. Depression is a disorder of decreased neuroplasticity. Recent evidences suggest that antidepressants act by enhancing neuroplasticity, which allows environmental inputs to modify the...

Author(s): Z. H. Zheng, Y. T. Zeng, J. H. Tao, J. J. Duan, T. Zhou and F. Xu

January 2014

Synergistic anticancer effects of valproic acid, atorvastatin and pioglitazone in human malignant and murine cells

Valproic acid, atorvastatin and pioglitazone belong to different therapeutic drug classes and exhibit biological activities that are capable of interfering with cancer development. In this study, we examined the anticancer synergistic effects of these three drugs in experimental models in vitro and in vivo. Cytotoxic activity was determined against K562, NCI-H292 and HEp-2 lines cells. The Ehrlich carcinoma was used as...

Author(s): André L. S. Barros, Jaciana S. Aguiar, Larissa C. C. Araújo, Christina A. Peixoto, Paloma L. de Medeiros, Maria Teresa J. A. Catanho and Teresinha Gonçalves da Silva