African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 15 May, 2014; 8(18)

May 2014

Hepatoprotective effect of Caesalpinia crista Linn. against CCl4 and paracetamol induced hepatotoxicity in albino rats

This study was done to investigate the hepatoprotective effect of extracts of Caesalpinia crista against carbon tetrachloride and paracetamol induced liver toxicity in albino rats. Seeds of C. crista were subjected to ethanolic and aqueous extraction. Albino rats were exposed to carbon tetrachloride (3 ml/kg rat b.w) and paracetamol (3 g/kg rat b.w) in two different protocols. Seven groups (n = 6) of animals were used...

Author(s):    Nakul Gupta, Prerna Chauhan, Maryam Nayeem, Mohammed M. Safhi and Meetu Agarwal   

May 2014

Bacterial meningitis: An update review

Bacterial meningitis is still considered serious life-threatening disease in spite of the decline in the morbidity and mortality in the last decade. The expeditious diagnosis of the disease, a prompt empiric antibiotic treatment and the proper adjunctive therapy are corner stones for the successful management of the disease. The objective of this review is to provide the health care professionals with an update of...

Author(s): Abdulkareem M. Al Bekairy, Shmeylan Al Harbi, Abdulmalik M. Alkatheri, Saleh Al Dekhail, Lolowa Al Swaidan and Nabil Khalidi

May 2014

Anti-oxidant vitamins, phytochemicals and proximate composition of the ethanol extract of the leaves of Musa paradisiaca

The leaves of Musa paradisiaca are used in the treatment of diverse ailments including diabetes mellitus and diarrhoea and hence, the anti-oxidant vitamins, phytochemicals and proximate composition of the ethanol extract of its leaves were investigated using standard methods. The results show that the concentrations of vitamins A, C and E in the extract were found to be 1.972 ± 0.013 μg/g, 0.686 ± 0.030...

Author(s): ENECHI Osmund C., ODO Christian E. and AGOSI Prince O.

May 2014

Preclinical evaluation of the crude extract from the fruits of Punica grantaum L. (Punicaceae) for antimicrobial activity in in vitro and ex vivo experimental models: A comparative study

Currently, natural products have been evaluated as sources of antimicrobial agents. Considering the increasing use of pomegranate, it has become important to establish a correlation between the phytocompounds and the antimicrobial properties of the crude extract used in Brazilian folklore medicine. The compositional analysis revealed the presence of classes of secondary metabolites of pharmaceutical interest, among...

Author(s): Andrey Pereira Lopes, Bianca Souza Bagatela, Virgínia Berlanga Campos Junqueira, Kleber Renê da Silva, Fernando Luiz Affonso Fonseca, and Fábio Ferreira Perazzo,