African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 22 June 2014; 8(23)

June 2014

Effect of pequi tree Caryocar coriaceum Wittm. leaf extracts on different mouse skin inflammation models: inference with their phenolic compound content

Caryocar coriaceum Wittm. (pequi) has been popularly used in Northeastern Brazil in the treatment of inflammation, pain and respiratory affections. This study evaluated the topical anti-inflammatory activity of C. coriaceum hydroethanolic extract (CCHE) and methanolic fraction (CCMF) from pequi tree leaves against different skin sensitizer agents (arachidonic acid, croton oil, phenol and histamine), as well their...

Author(s): Mariana K. A. Araruna, Rogério A. Saraiva, Pablo A. Nogara, João B. T. Rocha, Aline A. Boligon, Margareth L. Athayde, Lindaiane B. Rodrigues, Roger Henrique S. da Costa, Francisco Rafael A. Santana, José G. M. Costa, Henrique Douglas M. Coutinho, Patricia Gonçalves Pinheiro, Marta R. Kerntopf, Almir Gonçalves Wanderley and Irwin R. A. Menezes

June 2014

The mineral, proximate and phytochemical components of ten Nigerian medicinal plants used in the management of arthritis

Ethnobotanical investigation revealed the use of ten medicinal plants in the management of arthritis in Ibadan, Nigeria. This study screened the plants for mineral, proximate and phytochemical components that could be responsible for their therapeutic value in arthritis. The powdered plant samples were analysed for nutritional constituents and phytochemical compounds using standard laboratory protocols. The use value of...

Author(s): Gbadamosi, I. T. and Oloyede A. A.

June 2014

Design, synthesis and evaluation of the molluscicidal activity of novel hydrocarbyl substituted salicylic acid derivatives

Based on the molluscicidal activity of ginkgolic acids (GAs) isolated from Ginkgo biloba L and synthetic GA analogues, a series of long chain, substituted at 4 and 5 position, salicylic acid derivatives, including the Z/E isomers and their saturated derivatives, were prepared. Their molluscicidal activities against the host snail Oncomelania hupensis were evaluated. The acute fish toxicity against the wild-type...

Author(s): Zonglong Yang, Xiuyan Wang, Zuohua Mao, Yuan Lv, Jiahu Pan and Peizhong Yu

June 2014

Tynanthus micranthus: An efficient antioxidant and tyrosinase activity inductor

The aim of this paper was to evaluate the potential in vitro antioxidant activity of Tynanthus micranthus Corr. Mello ex Schum and its activity on tyrosinase, a melanogenesis-involved enzyme. The methods employed were 2,2- diphenyl-1-picril-hydrazyl  (DPPH),  phosphomolybdenum  complex,  catalase, peroxidase, superoxide dismutase (SOD), reduced glutathione (GSH) and mushroom tyrosinase activity...

Author(s): Fernanda Colombi Cansian, Cristiane Bezerra da Silva, Cristina Peitz de Lima, Francis José Zortéa Merino, Katlin Suellen Rech, Michel Fleith Otuki, Patrícia Mazureki Campos, Obdulio Gomes Miguel and Marilis Dallarmi Miguel