African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 22 September, 2014; 8(35)

September 2014

Formulation development of immediate release chlorpropamide tablets using directly compressible excipients

Diabetes mellitus is a major cause of morbidity and mortality worldwide. Chlorpropamide is an oral antidiabetic drug belonging to sulphonyl urea group, frequently prescribed in the treatment of type II diabetes mellitus. The present study was aimed on adopting cost effective direct compression method for the development of immediate release tablets of chlorpropamide by employing Avicel PH 102 and pregelatinized starch...

Author(s): Shahzad Ahmad, Muhammad Harris Shoaib , Rabia Ismail Yousuf , Wajiha Iffat, Sadia Shakeel, Najia Rahim, Riffat Yasmin, Rehana Bibi, Sadaf Ibrahimand Faisal Muhammad Khan

September 2014

In vitro effects of Eugenia pyriformis Cambess., Myrtaceae: Antimicrobial activity and synergistic interactions with Vancomycin and Fluconazole

The Eugenia pyriformis Cambess. species, Myrtaceae, also known by the popular name as uvaia was evaluated for its antimicrobial activity. Broth microdilution method was used to determine the Minimum Inhibitory Concentration (MIC) against selected pathogenic strains of bacteria, and fungi. Checkerboard method was used to evaluate the synergistic interactions of E. pyriformis with Vancomycin and Fluconazole. The leaf and...

Author(s): Angela Maria de Souza, Lorene Armstrong, Francis José Zortéa Merino, Laura Lúcia Cogo, Cristina Leise Bastos Monteiro, Márcia do Rocio Duarte, Obdulio Gomes Miguel and Marilis Dallarmi Miguel

September 2014

Technological development and evaluation on sialagogue activity of a spray-like liquid formulation of pilocarpine

Xerostomia is a common condition in patients undergoing oncological treatment. As a result of adverse effects of drugs or as an answer to radiotherapy radiation, the salivary glands of mouth stop or reduce the production and secretion of saliva. This leads to severe consequences such as caries, infections, difficulty in swallowing, and sensory loss. Thus, this work aimed to develop a new product to be used in patients...

Author(s): Giuliano André Silva Santos, Laisa Lis Fontinele de Sá, José Roberto de Souza de Almeida Leite, Rivelilson Mendes de Freitas and Lívio César Cunha Nunes