African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 29 April, 2014; 8(16)

April 2014

Comparative pharmacokinetic study of luteolin after oral administration of Chinese herb compound prescription JiMaiTong in spontaneous hypertensive rats (SHR) and Sprague Dawley (SD) rats

JiMaiTong (JMT), a Chinese herb compound prescription consisted of Flos chrysanthemi Indici, Spica prunellae and Semen cassiae for anti-hypertension. Luteolin is one of the major bioactivity compositions in F. chrysanthemi Indici in JMT. There are some reports about pharmacokinetics of luteolin in extract of F. chrysanthemi and husks of peanut in normal rats, but it lacked pharmacokinetic information of luteolin...

Author(s): Zhao-Huan Lou, Su-Hong Chen, Gui-Yuan Lv,Bo-Hou Xia, Mei-Qiu Yan, Zhi-Ru Zhang and Jian-Li Gao

April 2014

Clinical and microbiological effects of systemic ciprofloxacin and metronidazole in Aggregatibacter actinomycetemcomitans-associated periodontitis

Destructive periodontal disease is a concern because of the potential damage to the dentition and the financial burden of treatment. It is generally agreed that the microorganisms residing in periodontal pockets are responsible for periodontitis. Approximately 500 bacterial taxa inhabit periodontal pockets. Association between Aggregatibacter actinomycetemcomitans and destructive and progressive forms of periodontitis...

Author(s): Nasrin Esfahanizadeh, Soroosh Khalilinejad and Leyla Zonubi 

April 2014

Effect of Thespesia populnea Linn. on dexamethasone induced insulin resistance in mice

In traditional medicine, plants have been used to treat diabetes mellitus as valuable alternative therapy since synthetic oral hypoglycemic agents are known to exhibit adverse side effects. The present study was planned to investigate the effect of ethanolic extract of bark of Thespesia populnea Linn (TP) on plasma glucose, serum triglyceride and body weight in dexamethasone-induced insulin resistance in mice. The...

Author(s): Mohini A. Phanse, Manohar J. Patil and Konde Abbulu