African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 29 August, 2013; 7(32)

August 2013

The acute and long-term safety evaluation of aqueous, methanolic and ethanolic extracts of Achillea fragrantissima

This study was designed to explore the safety and side effects of the different extracts (water, ethanolic and methanolic) of Achillea fragrantissima given acutely or on repeated doses (125 and 250 mg/kg) in rats. Acute and subchronic toxicity, as well as reproductive (fertility, embryotoxicity and teratogenecity, peri-and postnatal study) effects were recorded on treated and control rats. Daily administration...

Author(s): M. A. Mandour, S. A. Al-Shami, M. M. Al-Eknah, Y. A. Hussein and I. M. El-Ashmawy,    

August 2013

Preliminary evaluation of the immunoenhancement potential of fowl typhoid vaccine formulated as an oral cationic liposome

Salmonella gallinarum is a non-motile host-specific bacterium in domestic poultry. It causes fowl typhoid, especially in domestic poultry. The study was performed with a view to compare the antibody titre of commercial subcutaneous Fowl typhoid® vaccine with its oral liposomal formulation. The chicken, divided into three groups (n = 20 per group), were inoculated via oral or subcutaneous route. Group...

Author(s): E.B. Onuigbo, D. M. Gyang and A. A. Attama      

August 2013

Effect of Hibiscus sabdariffa calyx extract on reproductive hormones in normal rats

Medicinal plants contain physiologically active principles that over the years had been exploited in traditional medicine for the treatment of various ailments. The present study was undertaken to investigate the effects of ethanolic extract of Hibiscus sabdariffa calyx on rat reproductive hormones. The effects on the basal levels of estradiol, testosterone, prolactin and follicle stimulating hormone were...

Author(s): Nizar Sirag, Elhadi M. Ahmed, Algaili M. Algaili, Hozeifa Mohamed  and Imad M. Tajeldeen    

August 2013

Effect of guava (Psidium guajava Linn.) fruit water extract on lipid peroxidation and serum lipid profiles of streptozotocin-nicotinamide induced diabetic rats

The prevalence of diabetes is rapidly increasing and it can cause a wide range of health complications affecting almost every part of the body. The aim of this study was to examine guava fruit ability in reducing blood glucose level and preventing diabetic complication ofstreptozotocin-nicotinamide induced diabetes rat. Guava fruit performance was measured byin vitro lipid peroxidation...

Author(s): Hsueh-Chin Chao, Po-Hua Wu, Diana Lo, Wan-Ting Wu and Ming-Chang Wu