African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 29 December, 2014; 8(48)

December 2014

Factors affecting physicians' prescription and pattern of prescription in the management of secondary infertility

The management of infertility is a medical and social need and the drugs are usually not in common use and are quite expensive. Several factors may affect choice of drugs and prescription pattern. This work assessed the factors that influence physicians’ prescribing decisions for this specialized condition and the prescription pattern in its management. Commonly prescribed drugs and prescribing indicators were...

Author(s): Rebecca Soremekun and Bukola Omitiran

December 2014

Synthesis, evaluation and molecular docking studies for the anti-inflammatory activity of novel 8-substituted-7-benzoyloxy-4-methyl-6-nitrocoumarin derivatives

Starting from the 8-acetyl-4-methyl-6-nitro-2-oxo-2H-chromen-7-yl benzoate I, 8-(3-arylacryloyl)-4-methyl-6-nitro-2-oxo-2H-chromen-7-yl benzoates (chalcones) II were synthesized and further used for the synthesis of two new series of 8-(2-imino/oxo/thioxo pyrimidin-4-yl)-4-methyl-6-nitro-2-oxo-2H-chromen-7-yl benzoates III-V and 8-(pyrazol-3-yl)-4-methyl-6-nitro-2-oxo-2H-chromen-7-yl benzoates VI and VII. All of the...

Author(s): Radwan El-Haggar, Ola Ahmed Abdel-Rasheed, Tamer Nasr, Hamed I. Ali, Ayman Goudah and Nageh Abotaleb

December 2014

Sensitive liquid chromatography-mass spectrometry determination of isoniazid: Elimination of matrix effects

Small size and high polar basic compounds have always been challenging with heavy matrix effect due to their difficult complete separation from polar endogenous compounds contained in most biological matrix. In this study, a relevant design including column choice, mobile phase constituents, and liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) parameters optimization have been developed to remove...

Author(s): Janvier Engelbert Agbokponto, Chuting Gong, Assogba Gabin Assanhou, Desmond Omane Acheampong, Raphael Nammahime Alolga, Yvane Nova Mfono-Oke and Li Ding            

December 2014

Neuropharmacological evaluation of selected Jordanian traditional herbal medicines

Numerous medicinal plants have been described in traditional medicine for treatment of dementias, including Alzheimer’s disease (AD). In this study, some of these plants were evaluated in three different types of pharmacological bioassays related to AD pathology to explore the possible mechanisms underpinning their traditional use. Six selected plants were extracted with ethanol and screened in vitro for...

Author(s): Sawsan Abuhamdah, Rushdie Abuhamdah, Ashok Shakya, Suleiman M. Al-Olimat and Paul Chazot