African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2183

Table of Content: 29 January, 2015; 9(4)

January 2015

Exploration of the neurotoxicity of ciprofloxcin or gatifloxacin single dose in rat cortex and hippocampus

The study aimed to evaluate the neurotoxicity of ciprofloxacin (Cip) or gatifloxacin (Gati) single oral dose in male albino rats weighing (100 ± 20 g) grouped as control-administered water, ciprofloxacin (80 mg/kg) and gatifloxacin (32 mg/kg) each of 12 rats. The frontal cortex of both groups revealed decrease in glutamate, GABA, taurine, histidine and serotonin levels and elevation of aspartate, glycin and...

Author(s): Nadia Mohamed Said Arafa, Sayed M. Rawi and Sara Abdullah Mubarak

January 2015

Drug use pattern in out-patient children: A comparison between primary and secondary health care facilities in Northern Nigeria

Children are more vulnerable to adverse events related to use of drugs. It is therefore important to study drug use in children in order to optimize pharmacotherapy. The aim of this study was to compare drug utilization in paediatric outpatient departments of primary and secondary health care facilities. The patient and drug information of 600 patients was analyzed for World Health Organization (WHO) recommended...

Author(s): Basheer A. Z. Chedi, Ibrahim Abdu-Aguye and Helen O. Kwanashie

January 2015

Performance, parasitic infections, hematology and hepatic histology of Colossoma macropomum (tambaqui) fed on homeopathic product

Homeopathic products may act in an organism by stimulating the immune system, allowing the restoration of balance and encouraging organic response under stress. This study investigated the performance, blood, morphological and parasitological parameters in Colossoma macropomum (tambaqui) fed diets containing different concentrations of Homeopatila 100®. Juvenile tambaqui underwent four treatments with three...

Author(s): Douglas Anadias Pinheiro, Bruno Adan Sagratzki Cavero, Lauro Vargas, Graciela Lucca Braccini, Eliane Tie Oba Yoshioka, Marcos Sidney Brito Oliveira and Marcos Tavares-Dias

January 2015

In vitro evaluation of the antibacterial activities of the methanol, aqueous and n-hexane extracts of Ocimum lamiifolium from Ethiopia

Ocimum lamiifolium (local name Dama Kesse, Amharic) is a medicinal plant in Ethiopia. Its leaves are squeezed and sniffed to treat coughs and colds. They are also used to treat eye infections and to stop nose bleedings. In the present study, leaves of O. lamiifolium were collected from their growing habitats. Dried leaf powders were extracted using methanol, distilled water and n-hexane.  25, 50, and 100 mg/ml...

Author(s): Destaw Damtie and Yalemtsehay Mekonnen

January 2015

Chemical composition of essential oils from the stem barks of Croton conduplicatus (Euphorbiaceae) native to the Caatinga biome

Croton conduplicatus is a species popularly known in the Brazilian Caatinga (semi-arid vegetation) as “quebra faca”. Essential oils from the stem barks of C. conduplicatus were obtained by hydrodistillation after 2, 3 and 4 h of extraction with a very high percentage (95.93, 96.69 and 98.45%, respectively) of identified total components present in crude essential oils. Analyses were made by gas...

Author(s): Jackson Roberto Guedes da Silva Almeida, Ana Valéria Vieira de Souza, Ana Paula de Oliveira, Uiliane Soares dos Santos, Maziele Dias de Souza, Luma dos Passos Bispo, Izabel Cristina Casanova Turatti and Norberto Peporine Lopes