African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 29 March, 2014; 8(12)

March 2014

Antibacterial effect of Royal gelly, mix from Royal jelly and rape honey (1:100), rape and oak honeydew honeys against Escherichia coli (ATCC 25922)

The Royal jelly (RJ), RJ and rape honey (HJ), rape (RH) and oak honeydew honey (HH) at concentrations of 10 to 45% were contaminated with 50 to 100 CFU/ml Escherichia coli ATCC 25922. After plating onto ChromoCult® TBX agar up to 30 min from contamination and after enrichment in Tryptic soy broth (TSB) at 37°C for 24 h, it revealed no visible colonies. These concentrations were defined as real bactericidal...

Author(s): Dinko Dinkov and Todor Stoyanchev

March 2014

Evaluation of anti-diarrheic properties of the aqueous methanolic extract of Palisota hirsuta leaves and its fractions using in vivo models

The anti-diarrheic effects of the methanolic leaf extract of Palisota hirsuta (LEP) were evaluated using castor oil-induced diarrhea model and charcoal meal model to evaluate small intestinal transit (SIT). The plant material was extracted using cold maceration with 70% methanol for 48 h and concentrated in vacuo and was fractionated using column chromatography. LEP yielded 8.77% w/w material and seven fractions after...

Author(s): Eke G. Ifeanyi and Anaga O. Aruh

March 2014

Pharmacological evaluation of Rumex vesicarius Linn leaf extract and fractions in rabbit gastrointestinal ailment

The aqueous-methanolic leaf extract and fractions of the Rumex vesicarius L. (Rv.Cr) was evaluated for the possible presence of spasmogenic and spasmolytic constituents to rationalize its traditional uses in gastrointestinal disorders. In rabbit jejunum, R. vesicarius caused a dose-dependent (0.03 to 0.3 mg/ml) weak stimulatory effect on spontaneous contractions, followed by relaxation at the next higher dose (1 mg/ml)....

Author(s): Imran Ahmad Khan, Abdul Aziz, Fatima Saqib, Shaukat Hussain Munawar, Zahid Manzoor and Muhammad Asif Raza

March 2014

In vivo antimalarial activity of crude aqueous leaf extract of Pyrenacantha staudtii against Plasmodium berghei (NK65) in infected mice

Antimalarial activity of the crude aqueous leaf extract of Pyrenacantha staudtii was evaluated using chloroquine-sensitive Plasmodium berghei infection in mice with an objective to finding scientific evidence for the use of the plant as traditional antimalarial remedy in Ido/Osi LGA of Ekiti state, Nigeria. The crude aqueous extract of P. staudtii Engl. (Icacinaceae) (100,...

Author(s): Olorunniyi, O. F. and O. A. Morenikeji

March 2014

The protective effect of Panax ginseng against chromium picolonate induced testicular changes

Chromium occurs in the environment mainly in two states, tri (Cr(III)) and hexavalent (Cr(VI)). Chromium(III) (e.g. chromium picolonate) is essential for proper insulin function and is required for normal protein, fat and carbohydrate metabolism, and is acknowledged as a dietary supplement. In this study, we investigated the possible antioxidative properties of Panax ginseng against chromium picolonate (CrPic)-induced...

Author(s): Rehab M. Elgharabawy and Ashraf M. Emara