African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 8 April, 2013; 7(13)

April 2013

Antispasmodic potential of leaves, barks and fruits of Zanthoxylum armatum DC

Zanthoxylum armatum is a well known food product used as antispasmodic in traditional medicine system. In the present research work, the phytochemical composition of the leaves, barks and fruits was carried out showing that all parts are good source of alkaloids, saponin, tannins and flavonoids. The ethanolic and n-hexane extracts were tested for their antispasmodic potential using rabbit ileum tissues. The...

Author(s): Barakat Barq Barkatullah, Muahmmad Ibrar, Niaz Ali, Naveed Muhammad and Rehmanullah

April 2013

Comparison of hydroxyethyl starch and succinylated gelatin in cadaver renal graft function in kidney-transplant recipients

Hydroxyethyl starch solution (HES) is increasingly used during kidney transplantation for compensation of hypovolemia. However, the advantages of HES remain unclear. This clinical trial compared the effect of administering 6% HES 130/0.4 and 4% succinylated gelatin (SG) for volume replacement on the rate of delayed graft function (DGF), the occurrence of sensitive markers of renal impairment, and peritransplantation...

Author(s): Bin Liu, Meihua Piao, Chunyan Zhou, Yaowen Fu and Chunsheng Feng 

April 2013

Evaluation of the phenolic and flavonoid contents and radical scavenging activity of three southern African medicinal plants

Warburgia salutaris (Bertol. F.) Chiovs, Rhoicissus tridentata (L.f.) Wild & Drum andTerminalia sericea (Burch. ex DC.), are widely used medicinal plants in southern Africa. The aim of the study was to determine the phenolic and flavonoid content and evaluate the antioxidant activity of the three medicinal plants. Total phenolic and flavonoid contents were determined...

Author(s): Steenkamp V., Nkwane O., van Tonder J., Dinsmore A., Gulumian M.,

April 2013

The clinical characteristics of anti-tuberculosis drug induced liver injury in 2457 hospitalized patients with tuberculosis in China

Anti-tuberculosis drug induced liver injury (ATDILI) ranks the first in all kinds of drug-induced liver injuries. ATDILI causes not only economic loss of public health system and patients, but also mental burden of patients, and often leads to treatment interruption or drug resistance. To investigate the clinical characteristics and predisposing factors of ATDILI, the clinical characteristics of 2457 hospital-admitted...

Author(s): Huiru An, Xueqiong Wu, Zhongyuan Wang, Jing Xu, Shaohua Zheng and Kun Wang

April 2013

Incidence, type and causes of dispensing errors: A study from the community pharmacy

This study was carried out to evaluate the incidence, type and potential causes of dispensing errors at a community pharmacy in Madrid, Spain. Every prescription was filled at the pharmacy, while the investigator present was inspected. Additionally, a sample of will-call prescriptions was inspected. Investigators compared the physician’s written order to the content and label of each new...

Author(s): Alina de las Mercedes Martínez Sánchez

April 2013

Study on mock strawberry extracts in-vitro anti-tumor activity

This study was aimed at investigating the anti-tumor effects of mock strawberry extracts on S180 tumor-bearing mice and exploring its action mechanism. Solid tumor mice models were made and drugs were administered based of grouping. The tumor bodies were used to measure the anti-tumor rate, the blood was used to measure the interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) contents in the...

Author(s): Zhang Lili, Zhang Lan#, Wang Xiangming, Gu Jinxia, Wang Xiaoyun, Li Xueqi and Xia Hongyuan

April 2013

Antibacterial activities, chemical constitutes and acute toxicity of Egyptian Origanum majorana L., Peganum harmala L. and Salvia officinalis L. essential oils

Natural products are still major sources of innovative therapeutic agents for various conditions, including infectious diseases. Origanum majorana L., Peganum harmala L. andSalvia officinalis L. oils had wide range uses as traditional medicinal plants in Egypt. The current study was designed to evaluate the antibacterial activity of O. majorana, P. harmalaand S....

Author(s): Samy A. Selim, Mohamed H. Abdel Aziz, Mona S. Mashait and Mona F. Warrad