May 2016
Incidence of polypharmacy in Alzheimer's disease elderly patients from Guarapuava City (Paraná, Brazil)
Alzheimer's disease (AD) affects a large portion of the elderly worldwide and is the most common dementia in this population. AD is usually accompanied by concurrent comorbidities leading to the simultaneous use of several drugs to improve the quality of life, which renders AD patients vulnerable to drug interactions and adverse reactions. This study assessed the frequency of polypharmacy based on comorbidities in...
May 2016
Evaluation of the antioxidant activity of the leaves, stem-barks extracts and fractions of Ochna schweinfurthiana F.Hoffm (Ochnaceae)
The present study evaluates the in vitro antioxidant activity of the leaves and stem-barks extracts and fractions of Ochna schweinfurthiana. To this effect, the different extracts were obtained by maceration in four solvents namely ethyl acetate, methanol, acetone and water- ethanol mixture (20-80). The methanol extract which exhibited the best antioxidant activity was partitioned in hexane and ethyl acetate. The ethyl...
May 2016
Larvicidal potential of Mikania glomerata SPRENGEL extract on Ancylostoma caninum larvae
Parasitic diseases are seen as indicators of a country’s socioeconomic development, constituting a major public health problem as they cause direct health problems related to the lack of piped water, no sewage system, and lack of orientation. Contamination by the geohelminth Ancylostoma spp, causes the Cutaneous larva migrans (CLM), also known as "sandworms", presenting skin lesions of linear and...
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