African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 8 October, 2018; 12(27)

October 2018

Physician prescription practice of antibiotics for upper respiratory tract infection at Kilimanjaro Christian Medical Centre Moshi, Tanzania

Upper respiratory tract infection occurs commonly in both children and adults and is a major cause of morbidity worldwide. Inappropriate antibiotic prescription for upper respiratory tract infections is associated with increasing antibiotic resistance, healthcare costs, adverse events, and poor patient outcomes. The objective of this study was to determine physician prescription practices of antibiotics for upper...

Author(s): Aisha Mavura, Geofrey N Sigalla, Florida Muro, Rosemary Malya,, Petro P. Nambunga, Noel Sam and Debora C. Kajeguka  

October 2018

Simple bioanalytical method development and validation of micronised Domperidone 20 mg tablets using LCMS-MS and its pharmacokinetic application in Healthy Indian Volunteers

The current investigation deals with an validated Liquid chromatography–mass spectrometry/mass spectrometry (LC-MS/MS) analytical method for the quantification of micronised domperidone in plasma of human volunteers. The validation of LC-MS/MS method was accomplished by evaluating the inter-day and intra-day precision and accuracy in a linear concentration range of 3.33-100 ng/ml. The entire study was an attempt...

Author(s): Mohi Iqbal Mohammed Abdul, Sabahuddin Siddique, Syed Ata Ur Rahman, Durdana Lateef, Shubhasis Dan and Anirbandeep Bose  

October 2018

Synthesis, characterization, and anticancer activity against human breast cancer cell-line T47D studies of metal ion Cu(II) complex with 2,4,5-triphenylimidazole ligand

The complex of metal ion Cu(II) with the ligand 2,4,5-trifenilimidazol has been successfully synthesized with mole ratio of metal and ligand 1:2 in N,N-dimethylformamide as a solvent. Complex synthesis results obtained green light crystalline solid. Complex absorbs UV-Vis light at 529 nm. Fourier transform infrared (FTIR) characterization results indicate occurrence of bonding of metals and ligand that is Cu-N in region...

Author(s): Teguh Hari Sucipto, Harsasi Setyawati, Irmina Kris Murwani and Fahimah Martak