October 2018
Physician prescription practice of antibiotics for upper respiratory tract infection at Kilimanjaro Christian Medical Centre Moshi, Tanzania
Upper respiratory tract infection occurs commonly in both children and adults and is a major cause of morbidity worldwide. Inappropriate antibiotic prescription for upper respiratory tract infections is associated with increasing antibiotic resistance, healthcare costs, adverse events, and poor patient outcomes. The objective of this study was to determine physician prescription practices of antibiotics for upper...
October 2018
Simple bioanalytical method development and validation of micronised Domperidone 20 mg tablets using LCMS-MS and its pharmacokinetic application in Healthy Indian Volunteers
The current investigation deals with an validated Liquid chromatography–mass spectrometry/mass spectrometry (LC-MS/MS) analytical method for the quantification of micronised domperidone in plasma of human volunteers. The validation of LC-MS/MS method was accomplished by evaluating the inter-day and intra-day precision and accuracy in a linear concentration range of 3.33-100 ng/ml. The entire study was an attempt...
October 2018
Synthesis, characterization, and anticancer activity against human breast cancer cell-line T47D studies of metal ion Cu(II) complex with 2,4,5-triphenylimidazole ligand
The complex of metal ion Cu(II) with the ligand 2,4,5-trifenilimidazol has been successfully synthesized with mole ratio of metal and ligand 1:2 in N,N-dimethylformamide as a solvent. Complex synthesis results obtained green light crystalline solid. Complex absorbs UV-Vis light at 529 nm. Fourier transform infrared (FTIR) characterization results indicate occurrence of bonding of metals and ligand that is Cu-N in region...
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