African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: April 2008; 2(2)

April 2008

Characterization of rat liver mitochondrial permeability transition pore by using mitochondrial swelling assay

The mitochondrial permeability transition (MPT) is considered to contribute substantially to the regulation of normal mitochondrial metabolism and plays as an important mediator of cell death. MPT is regulated in a tissue specific manner. The importance of this work is highlighted by the fact that knowledge regarding liver MPT may serve as important determinants of the physiological state of the liver. Our results...

Author(s): Manash K. Paul, ≡, Rajinder K≡  and Anup K. Mukhopadhyay

  • Article Number: EDD2BA631979

April 2008

Antioxidant and antimicrobial activities of the Pistacia lentiscus and Pistacia atlantica extracts

The antimicrobial activity and antioxidant properties of Pistacia lentiscus L. and Pistacia atlantica Desf (Anacardiaceae) leaves extracts were studied against eight bacteria, five moulds and yeast. A strong antifungal activity and a weak antibacterial activity were observed. They showed also a high reducing power capacity and a weak scavenging activity for superoxide anions (14.16 % for P....

Author(s): Nabila Benhammou, Fawzia Atik Bekkara and Tatjana Kadifkova Panovska

  • Article Number: 86CD3DD32024

April 2008

HPLC analysis of nicotinamide, pyridoxine, riboflavin and thiamin in some selected food products in Nigeria

Food fortification is an important tool for improving the health of the population. Motivated by this, the National Agency for Food and Drug Administration and Control (NAFDAC) has in the past few years embarked on a campaign to create this awareness. There has been varying degree of compliance to this, and so it is of utmost importance to know the food products that contribute significantly to the dietary vitamin B...

Author(s): Chimezie Anyakora, Ibukun Afolami, Teddy Ehianeta and Francis Onwumere

  • Article Number: 9FB88BC32055

April 2008

Preliminary studies of blood pressure lowering effect of Nauclea latifolia in rats

Roots of Nauclea latifolia are used in Nigeria for the treatment of hypertension. Ethanolic extract of the root of N. latifolia was administered to anaesthetised rats through the jugular vein while the blood pressure was measured through the carotid artery. The extract reduced systolic, diastolic, and mean arterial pressure in normotensive and in one kidney one clip hypertensive rats in a dose...

Author(s): Z. A. M. Nworgu+, D. N. Onwukaeme, A. J. Afolayan, F. C Ameachina and B. A. Ayinde

  • Article Number: 7E191C532108