December 2019

Anti-inflammatory and analgesic activities of extracts from Balanites aegyptiaca L. Delile (Balanitaceae) root bark: Plant used against liver diseases in Bukina Faso

Balanites aegyptiaca (L.) Del has been used in various traditional medicines against inflammation and pain. The aim of this study was to evaluate the enzymatic, anti-oedmeatous and analgesic activities of ethanolic and aqueous extracts of Balanites aegyptiaca (L.) Del root bark in mice. The extracts were tested in vitro for their ability to inhibit the enzymes cyclooxygenase (COX)-1 and COX-2, 15-lipoxygenase (LOX) and...

Author(s): Kadiatou Tata Traoré, Noufou Ouédraogo, Lazare Belemnaba, Gilchrist Abdoul Laurent Boly, Leïla Marie Esther W. Kabré, Constantin B. Atchadé, Mohamed B. Belemlilga, Sylvain Ilboudo, Marius Lompo, Sylvin Ouédraogo, André Tibiri and Innocent Pierre Guissou,  

December 2019

Therapeutic effectiveness assessment of antiviral drugs used in chronic hepatitis treatment in three Ivorian university hospitals

This work aims to evaluate the effectiveness of drugs used for the management of chronic viral hepatitis in the three major university hospitals in Abidjan. This is a retrospective cross-sectional descriptive study of 203 patients investigated for treatment protocols, patient parameters before and after treatment. It emerged that treatment with pegylated Interferon alpha 2a resulted in a significant decrease in viremia...

Author(s): Geneviève Amenan N’guessan-Irié, Emile Allah-Kouadio, Christiane Ella Kogbahonon Allouka, Steven Driga Tchekpa Paul Kohi, Bienvenu Oko Gnépéhi and  Gisèle N’doua Siransy-Kouakou,  

December 2019

Non-adherence to statins therapy and its impact on cardiac morbidity and mortality: A metanalysis

Dyslipidemia is a major risk factor for cardiovascular disease, the leading cause of death worldwide. Statins have been shown to significantly reduce morbidity and mortality in patients with coronary artery disease and in patients with hyperlipidemia. However, there is a significant gap between expected and actual benefits; this may be attributed to poor adherence to statin therapy. Literature search was conducted by...

Author(s): Zelalem Gebretsadik Anebo and Nurettin Abacioglu  

December 2019

Hepatoprotective and antioxidant activities of Pterocarpus santalinoides methanol leaf extract

This study evaluated the hepatoprotective and antioxidant activities (AA) of Pterocarpus santalinoides methanol leaf extract (PSMLE) on carbon tetrachloride (CCl4)-induced hepatotoxicity in albino rats. Thirty male albino rats randomly assigned into 6 groups (A – F) of 5 rats each were used for the in vivo study. Hepatotoxicity was induced in groups A – E using CCl4. Group A served as negative control....

Author(s): Thelma Ebele Ihedioha, Isaac Uzoma Asuzu, Aruh Ottah Anaga and John Ikechukwu Ihedioha