African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: May 2008; 2(3)

May 2008

The anticonvulsant and sedative properties of stems of Cissus quadrangularis in mice

Cissus quadrangularis Linn grows in Savannah areas in Africa (Cameroon, Mali, Mauritania, Senegal, etc). In traditional medicine, the plant is used to treat anorexia, asthma, sickle cells, colds, pains, malaria, asthma and as an analgesic. In vivo animal models of epilepsy (maximal electroshock, n-methyl -d-aspartate, pentylenetetrazol, isonicotinic hydrazid acid and strychnine -induced convulsions or turning...

Author(s): E. Ngo Bum, G. T Ngoupaye, E. Talla, T. Dimo, G. C. N Nkantchoua, M. M Pelanken, G. S Taiwe

  • Article Number: 68E84F232185

May 2008

Effects of Cucumis metuliferus E Mey. Ex Naud (Cucurbitaceae) fruit extract on some male reproductive parameters in adult rats

The effect of the extract of Cucumis metuliferus fruit on some male reproductive parameters was investigated in albino rats. The LD50 of the extract was above 5000 mg/kg body weight when administered orally. Histological studies showed that there was no remarkable change in the testes histology compare to the control. The effects on sperm cells showed a statistically significant (P<0.05) increase in...

Author(s): Noel N. Wannang, Nanloh S. Jimam, Steven S. Gyang, Bukata B. Bukar and  Saleh Gotom

  • Article Number: 872017832214

May 2008

Performance of starch obtained from Dioscorea dumetorium as disintegrant in sodium salicylate tablets

Starch obtained from Dioscorea dumetorium was employed as a disintegrant in Sodium Salicylate based tablets at concentrations of 5 –15 %w/w. Properties of the starch evaluated include: bulk and tapped densities, water uptake by capillarity, Hausner’s quotient and percent compressibility. Compound tablets were evaluated for hardness, friability, disintegration time and dissolution rate. Batches of...

Author(s): Ibezim, Emmanuel C., Ofoefule, Sabinus I, Omeje, Edwin O and Odo, U. E.

  • Article Number: 789F79C32252

May 2008

Citalopram in the treatment of depressive disorders: An open label, multicenter study in China

Results of randomized, placebo-controlled trials with the selective serotonin reuptake inhibitor citalopram suggest that this agent is safe and effective for the treatment of depressive disorders. We investigated the safety and efficacy of citalopram in the treatment of Chinese patients with depressive disorders. An 8-week, open-label, multicenter study evaluated the safety and efficacy of citalopram in the treatment of...

Author(s): Tianmei Si and Liang Shu

  • Article Number: AC7DA4B32306

May 2008

Current status of salt iodization and level of iodine nutrient in India

In India, Iodine Deficiency Disorders (IDD) are present throughout the country. Out of 282 districts surveyed by Government of India institutions like Indian Council of Medical Research and Central Goitre Survey Teams in different States and Union Territories, 241 have been found to be endemic for iodine deficiency disorders. Issues relating to the safety of Universal Salt Iodization were carefully examined by eminent...

Author(s): Umesh Kapil

  • Article Number: A92B3B032330