The present investigation aimed to evaluate the anti-emetic activity of some members of the family Euphorbiaceae of Lahore region. The selected plants were Euphorbia prostrata, Euphorbia splendens, Euphorbia hirta, Euphorbia helioscopia, Ricinus communis, Jatropha integerrima, Putranjiva roxburghii and Phyllanthus emblica. Anti-emetic activity was carried out by the preparation of aqueous extract of these plants. Anti-emetic investigations showed that aqueous extracts of E. prostrata, P. roxburghii and P. emblica have high potential to reduce the frequency of retching in CuSO4 induced emesis in four days old chicks. Frequency of retching after treatment of aqueous extracts of E. prostrata, P.a roxburghii and P. emblica were 24.8 ± 0.89, 17.4 ± 0.89, 15.2 ± 0.58, respectively, which statistically proved significant at p<0.01 from the control (87.2 ± 1.46, 82.6 ± 1.46, 82.6 ± 1.45, respectively) values.
Key words: Antiemetic, Euphorbiaceae, CuSO4.
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