Biotechnology and Molecular Biology Reviews

  • Abbreviation: Biotechnol. Mol. Biol. Rev.
  • Language: English
  • ISSN: 1538-2273
  • DOI: 10.5897/BMBR
  • Start Year: 2006
  • Published Articles: 101

Review

A review of the pharmacological aspects of Solanum nigrum Linn.

F. O. Atanu1*, U. G. Ebiloma1 and E. I. Ajayi2
1Department of Biochemistry, Kogi State University, Anyigba, Nigeria. 2Department of Biochemistry, Osun State University, Osogbo, Nigeria.
Email: [email protected]

  •  Accepted: 03 August 2010
  •  Published: 31 January 2011

Abstract

This article reviews, bridges the gap between the folkloric use of Solanum nigrumlinn. (Sn) and the results of evidence based experiments. Although Sn is a rich source of one of plants most dreaded toxins solanine, it has appreciably demonstrated its potential as a reservoir of antioxidants having hepatoprotective, anti-tumor, cytostatic, anti-convulsant, anti-ulcerogenic and anti-inflammatory effects. The review encompasses in-vitro, in vivo and clinical studies done on Sn, while examining whether or not correct scientific measures have been taken in generating experimental evidences for its traditional uses. This review would afford research scientist to know how much is known and what is left undone in the investigation of Sn.

 

Key words: Solanum nigrum, folklore medicine, anticancer, solanine.