Biotechnology and Molecular Biology Reviews

  • Abbreviation: Biotechnol. Mol. Biol. Rev.
  • Language: English
  • ISSN: 1538-2273
  • DOI: 10.5897/BMBR
  • Start Year: 2006
  • Published Articles: 101

Review

Co-culture: A great promising method in single cell protein production

Asmamaw Tesfaw
  • Asmamaw Tesfaw
  • Department of Molecular, Microbial and Cellular Biology, College of Natural Sciences, Addis Ababa University, P. O. Box 1176, Addis Ababa, Ethiopia
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Fassil Assefa*
  • Fassil Assefa*
  • Department of Molecular, Microbial and Cellular Biology, College of Natural Sciences, Addis Ababa University, P. O. Box 1176, Addis Ababa, Ethiopia
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  •  Received: 17 March 2014
  •  Accepted: 21 May 2014
  •  Published: 30 June 2014

Abstract

The term single cell protein (SCP) refers to the dried microbial cells or total protein extracted from pure microbial culture (algae, bacteria, filamentous fungi and yeasts) which serves as food or/and feed supplements. Different substrate and fermentation optimizations are being carried out to maximize SCP production. However, little attention was given to coculturing. SCPs are produced better using coculture than monoculture. This paper reviews the positive roles of coculture in SCP production. First, it results in better saccharification of substrates and efficient carbon source utilization. Second, filling substrate utilization gap is another contribution of coculture. Third, it upgrades biomass and enrich SCP with nutrients than monoculture. Fourth, it reduces fermentation time and production cost by reducing cost of substrate treatment.

Key words: Single cell protein, biomass, coculture, monoculture, mixed culture.