March 2012

Homocysteine-A potent modulator

Homocysteine is an amino acid and is an intermediate metabolite of methionine metabolism. It is metabolized by two pathways, the trans-methylation and trans-sulphuration. These processes rely on an adequate supply of vitamin B12 and B6 and folic acid. Deficiency of vitamin B12, B6 and folic acid can build up homocysteine level in blood stream. High homocysteine levels has been implicated in a variety of...

Author(s): Janani Kumar, Sowmiya Jayaraman and Nandhitha Muralidharan

March 2012

Key aspects of the mesenchymal stem cells (MSCs) in tissue engineering for in vitro skeletal muscle regeneration

Tissue engineering, directly associated with Biotechnology and Biomedical Sciences, is an emerging field of research and development. The main issue of tissue engineering is to precisely and safely regenerate or reconstruct injured tissues of skeletal muscle, bone, teeth, neural, cardiac, cartilage etc. One of the primary requirements for tissue engineering development is a constant source of supplementary stem cells...

Author(s): Biswadeep Chaudhuri and Krishna Pramanik