Educational Research and Reviews

  • Abbreviation: Educ. Res. Rev.
  • Language: English
  • ISSN: 1990-3839
  • DOI: 10.5897/ERR
  • Start Year: 2006
  • Published Articles: 1949

Short Communication

Synthesis of human haemoglobin by plants

ONYESOM, I.
Department of Medical Biochemistry, Delta State University, Abraka, Nigeria
Email: [email protected]

  •  Accepted: 10 February 2006
  •  Published: 30 April 2006

Abstract

 

Haemoglobin, Hb is the red, protein pigment in blood that transports oxygen round the body. Decreased quantity could lead to anaemia, and when the anaemic condition turns severe, blood transfusion becomes inevitable. However, the safety of human source has become questionable in recent times, and this has aroused the interest of scientists to search for alternative source(s). Interestingly, Agrobacterium tumefaciens, a soil bone, gram-negative bacterium has been discovered to integrate a segment of its Ti plasmid into plant chromosome through wounds. Workers thus, exploited this natural genetic engineering process to transfer Hb gene into plants. Evidence suggests that initial trials recorded some measure of success. Although, the nascent technology is still being refined, when fully developed it would reduce the fear and risk associated with the human source of blood for transfusion.
 
Key words: Haemoglobin, Agrobacterium tumefaciens, Ti-plasmid, anaemia