Abstract

Foot ulcers are a major source of morbidity and mortality for individuals suffering from diabetes mellitus. Currently, available treatments for these wounds are often ineffective, which can lead to the progression of these lesions to a point that requires amputation of the affected limb. Despite amputation, these individuals subsequently suffer from an increased risk of mortality. A novel therapy has been suggested to ameliorate diabetic foot ulcers. This treatment is chlorine dioxide, which is a broad-spectrum antimicrobial agent that is safe when administered in low doses. Three case reports are presented of individuals with diabetic foot ulcers who responded to treatment with chlorine dioxide.

Key words: Diabetes mellitus, diabetic foot ulcers, antimicrobial, wound healing.