International Journal of
Nutrition and Metabolism

  • Abbreviation: Int. J. Nutr. Metab.
  • Language: English
  • ISSN: 2141-2332
  • DOI: 10.5897/IJNAM
  • Start Year: 2009
  • Published Articles: 127

Full Length Research Paper

Toxicologic evaluation of a plant food concentrate

Palma Ann Marone
  • Palma Ann Marone
  • Eurofins, Product Safety Laboratories, 2394 Highway 130, Dayton, NJ 08810, USA.
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Mark Bauter
  • Mark Bauter
  • Eurofins, Product Safety Laboratories, 2394 Highway 130, Dayton, NJ 08810, USA.
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Hana Hofman-Hüther
  • Hana Hofman-Hüther
  • BSL Bioservice Scientific Laboratories GmbH, Behringstrasse 6/8, 82152 Planegg, Germany.
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Roland J. Gahler
  • Roland J. Gahler
  • Factors Group of Nutritional Companies Inc. R&D, 3655 Bonneville Place, Burnaby,British Columbia, Canada.
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Simon Wood
  • Simon Wood
  • Factors Group of Nutritional Companies Inc. R&D, 3655 Bonneville Place, Burnaby,British Columbia, Canada.University of British Columbia, Food, Nutrition and Health Program, Faculty of Land and Food Systems, Main Mall, Vancouver, British Columbia, Canada.
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  •  Accepted: 25 October 2011
  •  Published: 31 December 2011

Abstract

The present study evaluated the mutagenic and toxicologic potential of a proprietary greens product sold under the trade names: All Greens®, Enriching GreensÒGreengevity®. This is a plant food concentrate of berry and enriched greens extract. An in vitro bacterial reverse mutation assay, showed no toxic effects in any of the five tester strains used up to the highest dose group evaluated except for a weak mutation effect in tester strain TA 1537 at a concentration of 5,000 µg/plate without metabolic activation. No biologically relevant increases in revertant colony numbers of any of the five tester strains were observed. In a 14-day feeding study of dietary levels of 0, 1.25, 2.5 and 5.0% in rats, there were no adverse clinical, body weight, food consumption or macroscopic changes associated with the administration of this product.

 

Key words: All greens, toxicology, Ames, 14-day dietary study.