International Journal of
Physical Sciences

  • Abbreviation: Int. J. Phys. Sci.
  • Language: English
  • ISSN: 1992-1950
  • DOI: 10.5897/IJPS
  • Start Year: 2006
  • Published Articles: 2572

Full Length Research Paper

Study on expression of DLC-1 and p-FAK proteins in epithelial ovarian cancer

Liu HuiNa1,2, Shi HuiRong1*, Zhang HaiLing1, Wu KaiYuan1, Zhang RuiTao1 and Huang HaoLiang1
1Department of Obstetrics and Gynecology, the First Affiliated Hospital of Zhengzhou University, 450052, China. 2Department of Obstetrics and Gynecology, the Zhengzhou Central Hospital, 450007, China.
Email: [email protected]

  •  Accepted: 01 June 2011
  •  Published: 18 August 2011

Abstract

We investigated expression of DLC1 and p-FAK proteins in epithelial ovarian cancer using immunohistochemistry method. Results showed that low expression of DLC-1 gene and high expression of p-FAK gene might have a correlation with occurrence, metastasis and infiltration of epithelial ovarian cancer. They might play together an important role in occurrence and development of epithelial ovarian cancer.

 

Key words: Ovarian cancer, epithelial ovarian cancer, DLC-1, p-FAK.