Journal of
AIDS and HIV Research

  • Abbreviation: J. AIDS HIV Res.
  • Language: English
  • ISSN: 2141-2359
  • DOI: 10.5897/JAHR
  • Start Year: 2009
  • Published Articles: 283

Short Communication

Screening for the presence of Helicobacter pylori in stool of HIV- positive patients

Hossein Samadi Kafil
  • Hossein Samadi Kafil
  • Student Research Center, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran.
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Fatemeh Farahi Jahromi
  • Fatemeh Farahi Jahromi
  • Student Research Center, Faculty of Medicine, Tarbiat Modares University, Tehran, Iran.
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Bahareh Hajikhani
  • Bahareh Hajikhani
  • Avicenna Research institute, Shaheed Beheshti University of Medical sciences, Tehran, Iran.
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Shahin Najar Pirayeh
  • Shahin Najar Pirayeh
  • Department of Medical Bacteriology, School of Medicine, Tarbiat Modares University, Tehran, Iran.
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Mohammad Aghazadeh
  • Mohammad Aghazadeh
  • Infectious Disease and Tropical Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
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  •  Accepted: 24 February 2011
  •  Published: 30 April 2011

Abstract

Helicobacter Pylori is a bacillus that naturally colonizes humans, living in gastric mucus. Association of H. pylori colonization of stomach with chronic gastritis, peptic ulcer and gastric malignancies has been well documented. In this study, we aimed to find presence ofH. pylori in stool of HIV infected patients by PCR. 43 patients who had confirmed HIV-infection were subjected. Specific primers for hpaA (flagellar sheath adhesin) and ureB(urea amidohydrolase), of H. pylori were designed and, presence of the genome of H. pyloriinvestigated by PCR method. 35 of the patients (81.39%) had CD4+ count below 200 andH. pylori was found in 30 patients (69.76%). Results show from screening by H. pylori in stool of HIV-infected patients that prevalence of this bacterium in these patients is high. This prevalence is similar to prevalence of H. pylori in HIV-non infected population.

 

Key words: Helicobacter pylori, HIV, flagellar sheath adhesin (hpaA), urea amidohydrolase(ureB), gastric.