Journal of
AIDS and HIV Research

  • Abbreviation: J. AIDS HIV Res.
  • Language: English
  • ISSN: 2141-2359
  • DOI: 10.5897/JAHR
  • Start Year: 2009
  • Published Articles: 283

Full Length Research Paper

Short-term combined exercise training improves the health of HIV-infected patients

Eduard Tiozzo
  • Eduard Tiozzo
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Dushyantha Jayaweera
  • Dushyantha Jayaweera
  • Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Allan Rodriguez
  • Allan Rodriguez
  • Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Janet Konefal
  • Janet Konefal
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Angelica B. Melillo
  • Angelica B. Melillo
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA. Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Sarah Adwan
  • Sarah Adwan
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA. Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Lawrence Chen
  • Lawrence Chen
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Chad Parvus
  • Chad Parvus
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA. Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Miguel Figueroa
  • Miguel Figueroa
  • Medical Wellness Center, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Nicole Hodgson
  • Nicole Hodgson
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Judi M. Woolger
  • Judi M. Woolger
  • Department of Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Ronald Kanka
  • Ronald Kanka
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA. Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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Arlette Perry
  • Arlette Perry
  • Department of Kinesiology and Sport Sciences, School of Education, University of Miami, Miami, FL 33136, USA.
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John E. Lewis
  • John E. Lewis
  • Department of Psychiatry and Behavioral Sciences, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.Center for Complementary and Integrative Medicine, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
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  •  Accepted: 06 March 2013
  •  Published: 31 March 2013

Abstract

This study tested the benefits of combined aerobic and resistance exercise training (CARET) in HIV-infected individuals receiving antiretroviral therapy. Twenty-three human immunodeficiency virus (HIV)-infected men and women, predominantly of lower socioeconomic status (SES), were randomly assigned and completed 12 weeks of: (a) standard medical treatment plus CARET or (b) standard medical treatment only. At baseline and follow-up, immune functioning, metabolic variables, quality of life (QoL), physical characteristics, and physical fitness were measured. The control group showed a significant decrease in CD4+ T cell count (-16%, p<0.05), whereas the exercise group maintained a more stable count after the intervention (-3%, p=0.39). Furthermore, exercise participants showed significant improvements in waist circumference (-2%, p<0.05), fasting glucose (-16%, p<0.05), physical (+11%, p<0.03) and mental (+10%, p<0.02) QoL, estimated VO2max (+21%, p<0.01), upper body strength (+15%, p<0.05), and lower body strength (+22%, p<0.05). Our 12-week, supervised, moderate-intensity CARET program resulted in more stable CD4 count and significant health improvements in HIV-infected individuals of lower SES.

 

Key words: Antiretroviral therapy, aerobic and resistance exercise training, immune functioning, quality of life.