Journal of
Bioinformatics and Sequence Analysis

  • Abbreviation: J. Bioinform. Seq. Anal.
  • Language: English
  • ISSN: 2141-2464
  • DOI: 10.5897/JBSA
  • Start Year: 2009
  • Published Articles: 46

Full Length Research Paper

Computational characterization of providence virus non-structural proteins: Evolutionary and functional implications

Nakayinga Ritah
  • Nakayinga Ritah
  • Department of Biological Sciences, Faculty of Science, Kyambogo University, Kampala, Uganda.
  • Google Scholar

  •  Received: 09 January 2019
  •  Accepted: 27 March 2019
  •  Published: 31 March 2019


Bawden AL, Gordon KHJ, Hanzlik TN (1999). The specificity of Helicoverpaarmigera stunt virus infectivity. Journal of Inverterbrate Pathology 74(2):156-163.


Dorrington RA, Gorbalenya AE, Gordon KHJ, Lauber C, Ward VK (2011). Tetraviridae. In Virus Taxonomy: Classification and Nomenclature of Viruses: Ninth Report of the International Committee on Taxonomy of Viruses, Edited by King AMQ, Adams MJ, Carstens EB, Lefkowitz EJ. San Diego: Elsevier Academic Press pp. 1091-1102.


Herschlag D (1995). RNA chaperones and the RNA folding problem. Journal Biological Chemistry 270(36):20871-20874.


Jiwaji M, Short JR, Dorrington RA (2016). Expanding the host range of small insect RNA viruses: Providence virus (Carmotetraviridae) infects and replicates in a human tissue culture cell line. Journal General Virology 97(10):2763-2768.


Kim SH, Ryabov EV, Kalinina NO, Rakitina DV, Gillespie T, MacFarlane S, Haupt S, Brown JWS, Taliansky M (2007). Cajal bodies and the nucleolus are required for systemic infection of a plant virus. EMBO Journal 26(8):2169-2179.


Kemenesi G, Földes F, Zana B, Kurucz, K., Estók, P, Boldogh S, Görföl T, Bányai K, Oldal M, Jakab F (2016). Genetic Characterization of Providence Virus Isolated from Bat Guano in Hungary. Genome Announcements 4(3):e00403-16.


Luke GA, de Felipe P, Lukashev A, Kallioinen SE, Bruno EA, Ryan MD (2008). Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes. Journal General Virology 89(4):1036-1042.


Lupas AN, Gruber M (2005). The structure of alpha-helical coiled coils. Advances in Protein Chemistry 70:37-78.


McCartney AW, Greenwood JS, Fabian MR, White KA, Mullen RT (2005). Localization of the tomato bushy stunt virus replication protein p33 reveals a peroxisome-to-endoplasmic reticulum sorting pathway. Plant Cell 17:3513-3531.


Moore NF (1991). The Nudarelia β family of insect viruses (1991). Viruses of Invertebrates, 277-285. Edited by Kursak E, Mecel D, New York.


Panavas T, Hawkins CM, Panaviene Z, Nagy PD (2005). The role of the p33:p33/p92 interaction domain in RNA replication and intracellular localization of p33 and p92 proteins of cucumber necrosis tombusvirus. Virology 338(1):81-95.


Pringle FM, Johnson KN, Goodman CL, McIntosh AH, Ball LA (2003). Providence virus: a new member of the Tetraviridae that infects cultured insect cells. Virology 306(2):359-370.


Rajendran KS, Nagy PD (2004). Interaction between the replicase proteins of tomato bushy stunt virus in vitro and in vivo. Virology 326(2):250-261.


Rajendran KS, Nagy PD (2006). Kinetics and functional studies on interaction between the replicase proteins of tomato bushy stunt virus: requirement of p33: p92 interaction for replicase assembly. Virology 345(1):270-279.


Rajendran KS, Nagy PD (2003). Characterization of the RNA binding domains in the replicase proteins of tomato bushy stunt virus. Journal Virology 77(17):9244-9258.


Ryabov EV, Taliansk ME, Robinson DJ, Waterhouse PM, Murant AF, de Zoeten GA, Falk BW, Vetten HJ, Mark J Gibbs (2011). Umbraviridae. In: Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses, pp. 1191-1195. Edited by King AMQ, Adam MJ, Carstens EB, Lefkowitz EJ. San Diego: Elsevier Academic Press.


Scholthof K-BG, Scholthof HB, Jackson AO (1995). The tomato bushy stunt virus replicase proteins are coordinately expressed and membrane associated. Virology 208(1):365-369.


Short JR, Dorrington RA (2012). Membrane targeting of an alpha-like tetravirusreplicase is directed by a region within the RNA-dependent RNA polymerase domain. Journal General Virology 93:1076-1716.


Short JR, Knox C, Dorrington RA (2010). Subcellular localization and live-cell imaging of the Helicoverpaarmigerastunt virus replicase in mammalian and Spodoptera frugiperda cells. Journal General Virology 91:1514-1523.



Short JR, Nakayinga R, Hughes GE, Walter CT, Dorrington RA (2013). Providence virus (family: Carmotetraviridae) replicates vRNA in association with the Golgi apparatus and secretory vesicles. Journal General Virology 94:1073-1078.


Taliansky ME, Robinson DJ (2003). Molecular biology of umbraviruses phantom warriors. Journal General Virology 84:1951-1960.


Taliansky M, Roberts IM, Kalinina N, Ryabov EV, Raj SK, Robinson DJ, Oparka KJ (2003). An umbraviral protein, involved in long distance RNA movement, binds viral RNA and forms unique, protective ribonucleo protein complexes. Journal Virology 77(5):3031-3040.


Taliansky ME, Robinson DJ, Murant AF (1996). Complete nucleotide sequence and organisation of the RNA genome of groundnut rosette umbravirus. Journal General Virology 77(9):2335-2345.


Tompa P, Csermely P (2004). The role of structural disorder in the function of RNA and protein chaperons. FASEB Journal 18(11):1169-1175.


Walter CT, Pringle FM, Nakayinga R, de Felipe P, Ryan MD, Ball LA, Dorrington RA (2010). Genome organization and translation products of Providence virus: insight into a unique tetravirus. Journal General Virology 91(11):2826-2835.


Walter CT (2008). Establishment of experimental systems for studying the replication biology of providence virus. Rhodes University. PhD thesis.


Wang Y, Zhang X, Zhang H, Lu Y, Huang H, Dong X, Chen J, Dong J, Yang X, Hang H, Jiang T (2012). Coiled-coil networking shapes cell molecular machinery. Molecular Biology of the Cell 23(19):3911-3922.