Journal of
Computational Biology and Bioinformatics Research

  • Abbreviation: J. Comput. Biol. Bioinform. Res
  • Language: English
  • ISSN: 2141-2227
  • DOI: 10.5897/JCBBR
  • Start Year: 2009
  • Published Articles: 39

Full Length Research Paper

Theoretical analysis indicating that human genome is not a blueprint and that human oocytes have the instructions

Koichi Itoh
The Institute for Theoretical Molecular Biology, 21-13, Rokurokuso-cho, Ashiya, Hyogo, Japan 659-0011
Email: [email protected], [email protected]

  •  Accepted: 09 September 2010
  •  Published: 31 January 2011


Is human genome really a blueprint? If it is not a blueprint, how are human bodies constructed? This paper solves this hypothetical proposition. Firstly, it indicates 8 examples of important biological pathways and factors among house-keeping genes and proved that human genome is not a blueprint, but a storage of genes. Secondly, it proved that human oocytes have the instructions for development and differentiation. In this case, the study used opened public database for expression profile of human oocytes. It selected 12700 genes, which are expressed in human oocytes. Among 12700 genes, more than 800 genes which are related to development and differentiation are expressed. Here, the study shows that human genome is not a blueprint and human oocytes have the instructions.


Key words: Blueprint, gene expression, human genome, human oocytes, theoretical biology