Journal of
Computational Biology and Bioinformatics Research

  • Abbreviation: J. Comput. Biol. Bioinform. Res
  • Language: English
  • ISSN: 2141-2227
  • DOI: 10.5897/JCBBR
  • Start Year: 2009
  • Published Articles: 39

Short Communication

Functional equivalence between plant PRORP1 and bacterial RNase P Ribonucleic acid (RNA) raises questions on control and recognition mechanisms

Gennaro Auletta1*, Ivan Colagè1, Geoffrey Cook2, Paolo D’Ambrosio1, Miguel Ramón1 and Andrew Pinsent3
1Specialization Science and Philosophy, Pontifical Gregorian University; Rome, Italy. 2Department of Physiology, Development and Neuroscience, University of Cambridge, England. 3Ian Ramsey Centre, University of Oxford, Oxford, England.
Email: [email protected]

  •  Accepted: 19 July 2011
  •  Published: 30 September 2011


In this short communication we consider the recent results of the successful substitution of theEscherichia coli RNase P ribonucleic acid (RNA) with the Arabidopsis protein enzyme PRORP1. The interest of this result lies in the fact that a plant protein-only enzyme is able to rescue lethal knock-down of the RNA component of bacterial RNase P. Such findings raise interesting questions as well as theoretical hypotheses as to the control and recognition mechanisms at play in the experimental situation, thus emphasizing the importance of informational processes beside pure physical-chemical ones.


KeywordsArabidopsis thalianaE. coli, functional equivalence, information control, PRORP, RNase P RNA.