October 2018
Theoretical and conceptual derivation of threshold phenomena and metabolic switching models in a chemostat system
A chemostat cell culture is a polyphasic dispersed system. Three models using net transport and metabolization (T/M) kinetics of hyperbolic form have been described. The first uses only one metabolic pathway and has been studied under various conditions. The second uses two metabolic pathways, with either high or low affinity for the substrate. The third adds excretion of fermentative products to the pathways in model...