February 2022
Characterisation of induced mutagenicity via single-cell gel electrophoresis in RAW264.7 and Caco-2 cells by hydrogen peroxide
The need for a complementary short-term mutagenicity bioassay with robust endpoints to the Ames assay has become increasingly crucial to in order to avoid false negative results. The alternative short-term test (STT) used in conjunction with the Ames increases the validity and decreases the number of false positive outcomes. As a result, Caco-2 cells (Human intestinal epithelial cell model) and RAW264.7 cells...
