Journal of
Cell Biology and Genetics

  • Abbreviation: J. Cell Biol. Genet.
  • Language: English
  • ISSN: 2141-6516
  • DOI: 10.5897/JCBG
  • Start Year: 2010
  • Published Articles: 13

Table of Content: March 2013; 3(2)

March 2013

Blockade of Akt/mTOR pathway and enhancement of histone acetylation by PHI to induce cells apoptosis in prostate cancer PC3 cells

Mammalian target of rapamycin (mTOR) has merged an important therapeutic target for cancers. Our object is to demonstrate that phenyhexyle isothiocyanate (PHI), a synthetic isothiocyanate, blocked Akt/mTOR signaling in prostate cancer PC3 cell line, in addition to inhibited histone deacetylase to induce cell apoptosis. Apoptotic cells were measured by TUNEL assay. Histone acetylated H3, H4 and the protein of Akt...

Author(s): Zhiming Zhuang, Xudong Ma, Yiqun Huang, Zhouda Zheng, Yacai Zheng and Shaohong Jiang

March 2013

Genetic diversity evaluation of Paraschistura bampurensis (Nikolskii, 1900) in Shapour and Berim Rivers (Iran) using microsatellite markers

Paraschistura bampurensis is one of the species of genus Paraschistura. It is distributed in Iran and Pakistan freshwater. This paper reports a study carried out on genetic diversity and population structure of P. bampurensis in Shapour and Berim river basins, Iran. 100 samples of 50 fish each were collected from each river and were used. Microsatellite markers have been increasingly used in...

Author(s): Ghasem Askari and Ali Shabani