August 2010
Association of HLA-G 14bp insertion/deletion polymorphism with autoantibody production in patients with autoimmune rheumatic diseases
HLA-G is a non-classical HLA-class Ib molecule and has multiple immunoregulatory properties. A 14bp insertion/deletion polymorphism in the HLA-G gene has been suggested to influence the expression of HLA-G and then to associate with certain pathological conditions, including autoimmune diseases. The aim of study was to evaluate the possible association of the HLA-G 14bp insertion (+14bp) and deletion (-14bp)...
August 2010
Propranolol effect on proliferation and vascular endothelial growth factor secretion in human immunocompetent cells
Beta-blockers are widely used drugs in cardiovascular diseases. Propranolol is a non selective beta-adrenergic blocker extensively used in treatment of arrhythmias, hypertension and several other cardiac problems. The inhibitory effects of propranolol on tumor growth, inflammation and angiogenesis have been shown by many investigations. Peripheral blood mononuclear cells (PBMCs) play important role in...
