Journal of
Infectious Diseases and Immunity

  • Abbreviation: J. Infect. Dis. Immun.
  • Language: English
  • ISSN: 2141-2375
  • DOI: 10.5897/JIDI
  • Start Year: 2009
  • Published Articles: 87

Full Length Research Paper

Immunological outcomes of neverapin (NVP) versus efafrenz (EFV) based antiretroviral therapy (ART) regimen among children on ART: A study from Black Lion Hospital, Addis Ababa, Ethiopia

Abebe Sorsa
  • Abebe Sorsa
  • Asella College of Health Science, Arsi University, Asella, Ethiopia.
  • Google Scholar

  •  Received: 07 December 2017
  •  Accepted: 25 January 2018
  •  Published: 31 January 2018


Abebe S (2017). Predictors of Sub-Optimal CD4 Recovery during the First Six Months of Anti-Retroviral Treatment (ART) in HIV Infected Children: A Retrospective Cross Sectional Study from Tikur Anbessa Tertiary Hospital, Addis Ababa, Ethiopia. J. Blood Lymph 7(3). Available at: 



Ahoua L, Guenther G, Pinoges L, Anguzu P, Chaix ML, Le Tiec C, Balkan S, Olson D, Olaro C, Pujades-Rodríguez M (2009). Risk factors for virological failure and subtherapeutic antiretroviral drug concentrations in HIV-positive adults treated in rural northwestern Uganda. BMC. Infect. Dis. 9(1):81.


Asfaw A, Ali D, Eticha T, Alemayehu A, Alemayehu M, Kindeya F (2015). CD4 cell count trends after commencement of antiretroviral therapy among HIV-infected patients in Tigray, Northern Ethiopia: a retrospective cross-sectional study. PLoS One 10(3):e0122583.


Bacha T, Tilahun B, Worku A (2012). Predictors of treatment failure and time to detection and switching in HIV-infected Ethiopian children receiving first line anti-retroviral therapy. BMC Infec. Dis. 12(197).


Brian CZ, Phungula T, Zanoni HM, France H, Cook EF, Feeney ME (2012). Predictors of poor CD4 and weight recovery in HIV-infected children initiating ART in South Africa. PLoS One 7(3):e33611.


Chiappini E, Galli L, Tovo PA, Gabiano C, Lisi C, Bernardi S, Viganò A, Guarino A, Giaquinto C, Esposito S, Badolato R (2009). Five-year follow-up of children with perinatal HIV-1 infection receiving early highly active antiretroviral therapy. BMC. Infect. Dis. 9(140).


Crum-Cianflone NF, Roediger M, Eberly LE, Ganesan A, Weintrob A, Johnson E, Agan BK, Infectious Disease Clinical Research Program HIV Working Group (2011). Impact of Weight on Immune Cell Counts among HIV-Infected Persons. Clin. Vaccine Immunol. 18(6):940-946.


de Castilla DL, Verdonck K, Otero L, Iglesias D, Echevarría J, Lut L, Gotuzzo E, Seas C (2008). Predictors of CD4+ cell count response and of adverse outcome among HIV-infected patients receiving highly active antiretroviral therapy in a public hospital in Peru. Int. J. Infect. Dis. 12:325-331.


Diniz LMO, Maia MMM, Camargos LS, Amaral LC, Goulart EMA, Pinto JA (2011). Impact of HAART on growth and hospitalization rates among HIV-infected children. J. Pediatr. 87:131-137.


Doris MM, Wu AW, Martin F, Katamba A, Seeley J (2015). Quality of life in patients treated with first-line antiretroviral therapy containing nevirapine or efavirenz in Uganda: a prospective non-randomized study. BMC Heal. Ser. Res. 15 (292).


Eshun-Wilson I, Taljaard JJ, Nachega JB (2012). Sub-optimal CD4 T-lymphocyte responses among HIV infected patients who develop TB during the first year of ART. J. AIDS Clin. Res. 3(1).


Ethiopia Ministry of Health (2012). Guidelines for Pediatric HIV/AIDS Care and Treatment in Ethiopia.1st ed.


Gezie LD (2016). Predictors of CD4 count over time among HIV patients initiated ART in Felege Hiwot Referral Hospital, northwest Ethiopia: multilevel analysis. BMC Res Note 9(377).


Hai-Yin J, Zhang MN, Chen HJ, Yang Y, Deng M, Ruan B (2014). Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: a systematic review and meta-analysis. Int. J. Infect. Dis. 25:130-135.


Junwen Z, Dongchi Z (2014). Clinical, immunological, and virological outcomes of pediatric antiretroviral therapy in central China. BMC Res. Note 7(419).


Kate S, Brennan AT, Maskew M, Long L, Berhanu R, Sanne I, Fox MP (2014). The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa. J. Int. AIDS Soc. 17 (19065).


Kaufmann GR, Furrer H, Ledergerber B, Perrin L, Opravil M, Vernazza P, Cavassini M, Bernasconi E, Rickenbach M, Hirschel B, Battegay M (2005). Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/mL in HIV Type 1–Infected Individuals Receiving Potent Antiretroviral Therapy. Clin. Infect. Dis. 41(3):361-372.


Lapphra K, Vanprapar N, Chearskul S, Phongsamart W, Chearskul P, Prasitsuebsai W, Chokephaibulkit K (2008). Efficacy and tolerability of nevirapine-versus efavirenz-containing regimens in HIV-infected Thai children. Int. J. Infect. Dis. 12(6):e33-e38.


Madec Y, Szumilin E, Genevier C, Ferradini L, Balkan S, Pujades M, Fontanet A (2009). Weight gain at 3 months of antiretroviral therapy is strongly associated with survival: evidence from two developing countries. Aids 23(7):853-861.


Mihiretu MK, Desalegn TZ Berihun MZ (2014). Predictors of CD4 Count Changes after Initiation of Antiretroviral Treatment in university of Gondar Hospital, Gondar in Ethiopia. Clin. Res. HIV/ AIDS. 2(2).


Ojha CR, Shakya G, Dumre SP (2016). Virological and Immunological Status of the People Living with HIV/AIDS Undergoing ART Treatment in Nepal. Hind. BioMed. Res. Int. 10(7).


Puthanakit T, Kerr SJ, Ananworanich J, Bunupuradah T, Boonrak P, Sirisanthana V (2009). Pattern and Predictors of Immunologic Recovery in Human Immunodeficiency Virus-Infected Children Receiving Non-Nucleoside Reverse Transcriptase Inhibitor-Based Highly Active Antiretroviral Therapy. Pediatr. Infect. Dis. J. 28:488-492.


Reda AA, Biadgilign S, Deribew A, Gebre B, Deribe K (2013). Predictors of change in CD4 lymphocyte count and weight among HIV infected patients on anti-retroviral treatment in Ethiopia: A retrospective longitudinal study. PLoS One 8(4):e58595.


Tadesse A, Worku A, Kebede Y, Alemu K, Kasim A, Shkedy Z (2017). Choice of initial antiretroviral drugs and treatment outcomes among HIV-infected patients in sub-Saharan Africa: systematic review and meta-analysis of observational studies. Sys. Rev. 6(173).


Theophilus BK, Owusu M, Mutocheluh M, Nguah SB, Obeng-Baah J, Hanson C, Dompreh A. (2015). Pattern and predictors of immunologic recovery in HIV infected patients. BMC Res. Notes 8(1):413.


Yotebieng M, Van Rie A, Moultrie H, Meyers T (2010). Six-month gain in weight, height, and CD4 predict subsequent antiretroviral treatment responses in HIV-infected South African children. AIDS 24(1):139-146.


Zanoni BC, Thuli P, Holly M, Zanoni, Holly F (2012). Predictors of Poor CD4 and Weight Recovery in HIV-Infected Children Initiating ART in South Africa, Johannesberg: Minuteman press.