Journal of
Microbiology and Antimicrobials

  • Abbreviation: J. Microbiol. Antimicrob.
  • Language: English
  • ISSN: 2141-2308
  • DOI: 10.5897/JMA
  • Start Year: 2009
  • Published Articles: 166

Full Length Research Paper

Antimicrobial activities of total alkaloids extracted from some Nigerian medicinal plants

Department of Chemistry, Nigerian Defense Academy Kaduna, Kaduna State, Nigeria.
Email: [email protected]

  •  Accepted: 03 February 2011
  •  Published: 31 March 2011



The antimicrobial activity of the total alkaloids from five medicinal plants namely Jatropha curcas, Calotropis procera, Magifera indica, Carica papaya and Psidium guajava, commonly used in northern Nigeria for the treatment of various ailments was evaluated using disc diffusion assay. The extracts were used against three bacterial isolates and two fungal isolates includingStaphylococcus aureus, StreptococciLactobacillus spp.Actinomycetes and Candida albicans, respectively. The results obtained show that all the plants contains various level of alkaloids and an appreciable level of antimicrobial activities were observed at a concentration level of 6x10µg/cm3 indicating that the plants could be a potential source of alkaloids that may be used for the treatment of various microbial diseases caused by the tested organisms.


Key words: Antimicrobial activity, total alkaloids, medicinal plants