Journal of
Medical Laboratory and Diagnosis

  • Abbreviation: J. Med. Lab. Diagn.
  • Language: English
  • ISSN: 2141-2618
  • DOI: 10.5897/JMLD
  • Start Year: 2010
  • Published Articles: 55

Short Communication

Blood group serology analysis of one rare case of β-thalassemia major with cold autoantibodies and alloantibodies

Zhi-xin Song
  • Zhi-xin Song
  • Department of Clinical Laboratory, the 3rd Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong, China.
  • Google Scholar
Yong Zou
  • Yong Zou
  • Department of Blood Transfusion, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, Guangdong, China.
  • Google Scholar

  •  Received: 30 May 2016
  •  Accepted: 25 August 2016
  •  Published: 30 September 2016


Barros MM, Blajchman MA, Bordin JO (2010) .Warm autoimmune hemolytic anemia: recent progress in understanding the immunobiology and the treatment. Transfus. Med. Rev. 4(3):195-210.


Bass GF, Tuscano ET, Tuscano JM (2013). Diagnosis and classification of autoimmune hemolytic anemia. Autoimmun Rev. 13(4-5):560-564.


Cai R, Li L, Liang X, Liu Z, Su L, Li W, Zhu Q, Mo Q, Pan L, Ouyang H, Huang L, Xu X (2002). Prevalence survey and molecular characterization of alpha and beta thalassemia in Liuzhou city of Guangxi. Zhonghua Liu Xing Bing Xue Za Zhi. 23(4):281-285.


Cheng CK, Lee CK, Lin CK (2012). Clinically significant red blood cell antibodies in chronically transfused patients: a survey of Chinese thalassemia major patients and literature review. Transfusion 52(10):2220-2224.


Cohen AR, Galanello R, Pennell DJ, Cunningham MJ, Vichinsky E (2004). Thalassemia. Hematology Am. Soc. Hematol. Educ. Program. 2004:14-34.


Higgins VL (1996). Leukocyte-reduced blood components: patient benefits and practical applications. Oncol. Nurs. Forum. 23(4):659-667.


Huang K, Fang JP, Zhou DH, Chen C, Huang SL, Xu HG, Li Y (2005). Clinical study of ten patients with beta-thalassemia major compl icated by immune-mediated hemolytic anemia. J. Clin. Hematol. 18(1):3-6. (In Chinese)


Lombardi G, Matera R, Minervini MM, Cascavilla N, D'Arcangelo P, Carotenuto M, Di Giorgio G, Musto P (1994). Serum levels of cytokines and soluble antigens in poly transfused patients with beta-thalassemia major: relationship to immune status. Haematologica 79(5):406-412.


Meulenbroek EM, Wouters D, Zeerleder SS (2015).Lyse or not to lyse: Clinical significance of red blood cell autoantibodies. Blood Rev. 29(6):369-376.


Miyaji K, Miyamoto T, Kohira S, Itatani K, Tomoyasu T, Sato H, Ohara K (2010). The effectiveness of prestorage leukocyte-reduced red blood cell transfusion on perioperative inflammatory response with a miniaturized biocompatible bypass system. J. Thorac. Cardiovasc. Surg. 139(6):1561-1567.


Moshtaghi-Kashanian GR, Gholamhoseinian A, Hoseinimoghadam A, Rajabalian S (2006). Splenectomy changes the pattern of cytokine production in beta-thalassemic patients. Cytokine 35(5-6):253-257.


Sadeghian MH, Keramati MR, Badiei Z, Ravarian M, Ayatollahi H, Rafatpanah H, Daluei MK (2009). Alloimmunization among transfusion-dependent thalassemia patients. Asian. J. Transfus. Sci. 3(2):95-98.


Sharma AD, Sreeram G, Erb T, Grocott HP, Slaughter TF (2000). Leukocyte-reduced blood transfusions: perioperative indications, adverse effects, and cost analysis. Anesth Analg. 90(6):1315-1323.


Vichinsky E, Butensky E, Fung E, Hudes M, Theil E, Ferrell L, Williams R, Louie L, Lee PD, Harmatz P (2005). Comparison of organ dysfunction in transfused patients with SCD or beta thalassemia. Am. J. Hematol. 80(1):70-74.


Vichinsky EP (2005). Changing patterns of thalassemia worldwide. Ann. N Y Acad. Sci.1054:18-24


Wang SC, Lin KH, Chern JP, Lu MY, Jou ST, Lin DT, Lin KS (2003). Severe bacterial infection in transfusion-dependent patients with thalassemia major. Clin. Infect. Dis. 37(7):984-988.


Xu XM, Zhou YQ, Luo GX, Liao C, Zhou M, Chen PY, Lu JP, Jia SQ, Xiao GF, Shen X, Li J, Chen HP, Xia YY, Wen YX, Mo QH, Li WD, Li YY, Zhuo LW, Wang ZQ, Chen YJ, Qin CH, Zhong M (2004). The prevalence and spectrum of alpha and beta thalassaemia in Guangdong Province: implications for the future health burden and population screening. J. Clin. Pathol. 57(5):517-522.