Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3672

Full Length Research Paper

Antimicrobial activity of Annona crassiflora Mart. against Candida albicans

Amaro de Mendonça Cavalcante
  • Amaro de Mendonça Cavalcante
  • Instituto de Química e Biotecnologia-Universidade Federal de Alagoas–57072-000 –Maceió-AL, Brasil
  • Google Scholar
Karlos Antonio Lisboa Ribeiro Junior
  • Karlos Antonio Lisboa Ribeiro Junior
  • Instituto de Química e Biotecnologia-Universidade Federal de Alagoas–57072-000 –Maceió-AL, Brasil
  • Google Scholar
Eulália CameloPessoa de Azevedo Ximenes
  • Eulália CameloPessoa de Azevedo Ximenes
  • Departamento de Antibióticos-Universidade Federal de Pernambuco-57040-521-Recife-PE, Brasil
  • Google Scholar
Zenaldo Porfirio Silva
  • Zenaldo Porfirio Silva
  • Laboratório de Microbiologia, Universidade Estadual de Ciências da Saúde de Alagoas. Campus Governador Lamenha Filho. 57010-382 Maceió-AL, Brasil
  • Google Scholar
José Ivo Limeira dos Reis
  • José Ivo Limeira dos Reis
  • Faculdade de Odontologia – Universidade Federal de Alagoas-57072-000-Maceió-AL, Brasil
  • Google Scholar
Antonio Euzebio Goulart de Santana
  • Antonio Euzebio Goulart de Santana
  • Instituto de Química e Biotecnologia-Universidade Federal de Alagoas–57072-000 –Maceió-AL, Brasil
  • Google Scholar


  •  Received: 09 January 2017
  •  Accepted: 10 March 2017
  •  Published: 03 April 2017

Abstract

This study evaluated the antimicrobial activity of the ethanol extract of Annona crassiflora Mart., against the fungus, Candida albicans present in the oral microbiota. The tests showed that the fractions of ethanol extract of the root bark and wood root of A. crassiflora showed a positive result. Of the strains studied, three showed sensitivity to 12 fractions and sub-fractions of A. crassiflora (66%). In the strains studied, strain 05 was the one that proved the most sensitive statistically (p <0.05). Their structures were determined using spectral techniques (NMR 1H and 13C) and based on literature data.

 

Key words: Annona classiflora, Candida albicans, antimicrobial activity.